| Literature DB >> 9279066 |
Abstract
Osteocalcin and matrix Gla protein (MGP) are two vitamin K-dependent proteins present in bone and cartilage. Transgenic mice models were recently developed to isolate the function of each of these proteins. While osteocalcin-deficient mice have increased bone formation, MGP-deficient mice have abnormal calcification leading to osteopenia, fractures, and premature death owing to arterial calcification.Entities:
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Year: 1997 PMID： 9279066 DOI： 10.1111/j.1753-4887.1997.tb01619.x
Source DB: PubMed Journal: Nutr Rev ISSN： 0029-6643 Impact factor: 7.110