Literature DB >> 9276239

A pseudo-outbreak of purified protein derivative skin-test conversions caused by inappropriate testing materials.

J C Grabau1, D J Burrows, M L Kern.   

Abstract

OBJECTIVE: To investigate a cluster of newly identified tuberculosis infections.
DESIGN: A field study was conducted including interviews; medical record reviews; checking of bills and invoices, pharmacy records, and drug manufacturer information; and clinical retesting.
SETTING: Community residential facilities providing comprehensive services to retarded adults. PARTICIPANTS: Twenty residential facility staff (not previously known to be purified protein derivative [PPD] positive).
RESULTS: Staff had been tested with 250 TU of PPD, and 9 of 20 were tuberculin positive. Retesting with 5 TU yielded no reaction.
CONCLUSIONS: Reactions were attributable to testing with a product not recommended for routine PPD screening. Healthcare workers planting PPD Mantoux tests always should check the vials to ensure that the appropriate strength solution is being used.

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Year:  1997        PMID: 9276239     DOI: 10.1086/647674

Source DB:  PubMed          Journal:  Infect Control Hosp Epidemiol        ISSN: 0899-823X            Impact factor:   3.254


  1 in total

1.  Strength of Tuberculin Used in the Mantoux Test: Does It Make a Difference?

Authors:  Joseph L Mathew
Journal:  Indian J Pediatr       Date:  2017-08-11       Impact factor: 1.967

  1 in total

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