Literature DB >> 9275702

The observation of complement activation and polymorphonuclear neutrocytopenia during cardiopulmonary bypass.

D Wang1, P Fu, J Cai, H Lan.   

Abstract

By determining the plasma levels of C2, C4, factor B and polymorphonuclear neutrophils (PMNs) of the patients who received CPB, the path of complement activation and changes of PMNs were studied. The results suggest that complement system was activated through alternative pathway during CPB and was activated through classic pathway after CPB. The anaphylatoxin, the products of complement activation may be responsible for the polymorphonuclear neutrocytopenia.

Entities:  

Mesh：

Substances：

Year:  1996        PMID： 9275702     DOI： 10.1007/bf02887967

Source DB:  PubMed          Journal:  J Tongji Med Univ        ISSN： 0257-716X


  8 in total

1.  Pulmonary injury secondary to extracorporeal circulation. An ultrastructural study.

Authors:  N B Ratliff; W G Young; D B Hackel; E Mikat; J W Wilson
Journal:  J Thorac Cardiovasc Surg       Date:  1973-03       Impact factor: 5.209

2.  Evidence for complement activation by protamine-heparin interaction after cardiopulmonary bypass.

Authors:  N C Cavarocchi; H V Schaff; T A Orszulak; H A Homburger; W A Schnell; J R Pluth
Journal:  Surgery       Date:  1985-09       Impact factor: 3.982

3.  Neutrophil-endothelial cell interactions. Modulation of neutrophil adhesiveness induced by complement fragments C5a and C5a des arg and formyl-methionyl-leucyl-phenylalanine in vitro.

Authors:  M G Tonnesen; L A Smedly; P M Henson
Journal:  J Clin Invest       Date:  1984-11       Impact factor: 14.808

4.  Complement activation during cardiopulmonary bypass: evidence for generation of C3a and C5a anaphylatoxins.

Authors:  D E Chenoweth; S W Cooper; T E Hugli; R W Stewart; E H Blackstone; J W Kirklin
Journal:  N Engl J Med       Date:  1981-02-26       Impact factor: 91.245

5.  Complement activation during cardiopulmonary bypass. Comparison of bubble and membrane oxygenators.

Authors:  N C Cavarocchi; J R Pluth; H V Schaff; T A Orszulak; H A Homburger; E Solis; M P Kaye; M S Clancy; J Kolff; G M Deeb
Journal:  J Thorac Cardiovasc Surg       Date:  1986-02       Impact factor: 5.209

6.  Neutrophil leukotriene generation increases after cardiopulmonary bypass.

Authors:  D Gadaleta; A L Fahey; M Verma; W Ko; K H Kreiger; O W Isom; J M Davis
Journal:  J Thorac Cardiovasc Surg       Date:  1994-10       Impact factor: 5.209

7.  Demonstration of specific C5a receptor on intact human polymorphonuclear leukocytes.

Authors:  D E Chenoweth; T E Hugli
Journal:  Proc Natl Acad Sci U S A       Date:  1978-08       Impact factor: 11.205

8.  Cytokine and complement levels in patients undergoing cardiopulmonary bypass.

Authors:  J B Steinberg; D P Kapelanski; J D Olson; J M Weiler
Journal:  J Thorac Cardiovasc Surg       Date:  1993-12       Impact factor: 5.209
  8 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.