Literature DB >> 9271858

Identification and characterization of an aadB gene cassette at a secondary site in a plasmid from Acinetobacter.

H Segal1, B G Elisha.   

Abstract

Transformation studies showed that an aminoglycoside resistance gene, aadB, is carried on a 6.0-kb plasmid (pRAY) in a clinical isolate of Acinetobacter (strain SUN). The gene was cloned and sequenced. An analysis of the DNA sequencing data showed that although the aadB gene is part of cassette, it is not associated with an integron. Rather, the aadB cassette has recombined at a secondary site downstream of putative promoters on pRAY.

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Year:  1997        PMID： 9271858     DOI： 10.1111/j.1574-6968.1997.tb12591.x

Source DB:  PubMed          Journal:  FEMS Microbiol Lett        ISSN： 0378-1097            Impact factor:   2.742


  7 in total

1.  Identification of a complete dfrA14 gene cassette integrated at a secondary site in a resistance plasmid of uropathogenic Escherichia coli from Nigeria.

Authors:  Kayode K Ojo; Corinna Kehrenberg; Stefan Schwarz; H Akin Odelola
Journal:  Antimicrob Agents Chemother       Date:  2002-06       Impact factor: 5.191

2.  Efficiency of recombination reactions catalyzed by class 1 integron integrase IntI1.

Authors:  C M Collis; G D Recchia; M J Kim; H W Stokes; R M Hall
Journal:  J Bacteriol       Date:  2001-04       Impact factor: 3.490

3.  Type 1 integrons in epidemiologically unrelated Acinetobacter baumannii isolates collected at Spanish hospitals.

Authors:  A Ribera; J Vila; F Fernández-Cuenca; L Martínez-Martínez; A Pascual; A Beceiro; G Bou; J M Cisneros; J Pachón; J Rodríguez-Baño
Journal:  Antimicrob Agents Chemother       Date:  2004-01       Impact factor: 5.191

4.  The IntI1 integron integrase preferentially binds single-stranded DNA of the attC site.

Authors:  M V Francia; J C Zabala; F de la Cruz; J M García Lobo
Journal:  J Bacteriol       Date:  1999-11       Impact factor: 3.490

5.  Reconstruction of an active integron recombination site after integration of a gene cassette at a secondary site.

Authors:  H Segal; M V Francia; J M Lobo; G Elisha
Journal:  Antimicrob Agents Chemother       Date:  1999-10       Impact factor: 5.191

Review 6.  Versatility of aminoglycosides and prospects for their future.

Authors:  Sergei B Vakulenko; Shahriar Mobashery
Journal:  Clin Microbiol Rev       Date:  2003-07       Impact factor: 26.132

7.  Novel Aminoglycoside Resistance Transposons and Transposon-Derived Circular Forms Detected in Carbapenem-Resistant Acinetobacter baumannii Clinical Isolates.

Authors:  Nabil Karah; Chinmay Kumar Dwibedi; Karin Sjöström; Petra Edquist; Anders Johansson; Sun Nyunt Wai; Bernt Eric Uhlin
Journal:  Antimicrob Agents Chemother       Date:  2016-01-11       Impact factor: 5.191
  7 in total

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