Literature DB >> 9270380

Decursinol angelate: a cytotoxic and protein kinase C activating agent from the root of Angelica gigas.

K S Ahn, W S Sim, I K Lee, Y B Seu, I H Kim.   

Abstract

A cytotoxic compound was purified from the root of Angelica gigas Nakai by normal phase HPLC. As a result of the structure analysis by mass, IR, 1H-NMR, and 13C-NMR spectrometry, the compound was identified as decursinol angelate, a structural isomer of decursin, and characterized originally from Sesei grandivittatum. Decursinol angelate showed in vitro cytotoxicity and protein kinase C activating activities like decursin.

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Year:  1997        PMID: 9270380     DOI: 10.1055/s-2006-957701

Source DB:  PubMed          Journal:  Planta Med        ISSN: 0032-0943            Impact factor:   3.352


  10 in total

1.  Ethanol extract of Angelica gigas inhibits croton oil-induced inflammation by suppressing the cyclooxygenase - prostaglandin pathway.

Authors:  Sunhee Shin; Seong Soo Joo; Dongsun Park; Jeong Hee Jeon; Tae Kyun Kim; Jeong Seon Kim; Sung Kyeong Park; Bang Yeon Hwang; Yun-Bae Kim
Journal:  J Vet Sci       Date:  2010-03       Impact factor: 1.672

2.  Anti-Inflammatory Effect of Angelica gigas via Heme Oxygenase (HO)-1 Expression.

Authors:  Joon Hyeong Cho; Jung Eun Kwon; Youngmi Cho; Inhye Kim; Se Chan Kang
Journal:  Nutrients       Date:  2015-06-15       Impact factor: 5.717

3.  Anti-cancer activity of Angelica gigas by increasing immune response and stimulating natural killer and natural killer T cells.

Authors:  Seo Hyun Kim; Sung Won Lee; Hyun Jung Park; Sang Hee Lee; Won Kyun Im; Young Dong Kim; Kyung Hee Kim; Sang Jae Park; Seokmann Hong; Sung Ho Jeon
Journal:  BMC Complement Altern Med       Date:  2018-07-18       Impact factor: 3.659

4.  Chemical and biological assessment of angelica roots from different cultivated regions in a chinese herbal decoction danggui buxue tang.

Authors:  Wendy L Zhang; Ken Y Z Zheng; Kevin Y Zhu; Janis Y X Zhan; Cathy W C Bi; J P Chen; Tina T X Dong; Roy C Y Choi; David T W Lau; Karl W K Tsim
Journal:  Evid Based Complement Alternat Med       Date:  2013-02-05       Impact factor: 2.629

5.  Decursin and decursinol angelate inhibit estrogen-stimulated and estrogen-independent growth and survival of breast cancer cells.

Authors:  Cheng Jiang; Junming Guo; Zhe Wang; Bingxiu Xiao; Hyo-Jung Lee; Eun-Ok Lee; Sung-Hoon Kim; Junxuan Lu
Journal:  Breast Cancer Res       Date:  2007       Impact factor: 6.466

6.  The Anti-Inflammatory Effects of a New Herbal Formula (WSY-1075) in a Nonbacterial Prostatitis Rat Model.

Authors:  Byung Il Yoon; Woong Jin Bae; Su Jin Kim; Hyo Sin Kim; U Syn Ha; Dong Wan Sohn; Sung-Yeoun Hwang; Sae Woong Kim
Journal:  World J Mens Health       Date:  2013-08-31       Impact factor: 5.400

7.  Bo-Gan-Whan regulates proliferation and migration of vascular smooth muscle cells.

Authors:  Kang Pa Lee; Jai-Eun Kim; Hyuck Kim; Hae Ryong Chang; Dae Won Lee; Won-Hwan Park
Journal:  BMC Complement Altern Med       Date:  2016-08-22       Impact factor: 3.659

Review 8.  Natural Korean Medicine Dang-Gui: Biosynthesis, Effective Extraction and Formulations of Major Active Pyranocoumarins, Their Molecular Action Mechanism in Cancer, and Other Biological Activities.

Authors:  Chinreddy Subramanyam Reddy; Seong Cheol Kim; Mok Hur; Yeon Bok Kim; Chun Geon Park; Woo Moon Lee; Jae Ki Jang; Sung Cheol Koo
Journal:  Molecules       Date:  2017-12-07       Impact factor: 4.411

9.  Decursin negatively regulates LPS-induced upregulation of the TLR4 and JNK signaling stimulated by the expression of PRP4 in vitro.

Authors:  Muhammad Bilal Ahmed; Salman Ul Islam; Young Sup Lee
Journal:  Anim Cells Syst (Seoul)       Date:  2020-02-17       Impact factor: 1.815

10.  Synthesis and Evaluation of Anticancer Activity of New 4-Acyloxy Derivatives of Robustic Acid.

Authors:  Rui Chen; Lini Huo; Yogini Jaiswal; Jianhua Wei; Dianpeng Li; Jing Zhong; Leonard Williams; Xing Xia; Yan Liang
Journal:  Int J Mol Sci       Date:  2019-10-26       Impact factor: 5.923

  10 in total

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