Literature DB >> 9270303

Caspases: killer proteases.

D W Nicholson1, N A Thornberry.   

Abstract

Caspases (cysteinyl aspartate-specific proteinases) mediate highly specific proteolytic cleavage events in dying cells, which collectively manifest the apoptotic phenotype. The key and central role that these enzymes play in a biochemical cell-suicide pathway has been conserved throughout the evolution of multicellular eukaryotes.

Mesh：

Substances：

Year:  1997        PMID： 9270303     DOI： 10.1016/s0968-0004(97)01085-2

Source DB:  PubMed          Journal:  Trends Biochem Sci        ISSN： 0968-0004            Impact factor:   13.807


  435 in total

1.  Release of cytochrome c, Bax migration, Bid cleavage, and activation of caspases 2, 3, 6, 7, 8, and 9 during endothelial cell apoptosis.

Authors:  D J Granville; J R Shaw; S Leong; C M Carthy; P Margaron; D W Hunt; B M McManus
Journal:  Am J Pathol       Date:  1999-10       Impact factor: 4.307

2.  Role of factors downstream of caspases in nuclear disassembly during apoptotic execution.

Authors:  K Samejima; P Villa; W C Earnshaw
Journal:  Philos Trans R Soc Lond B Biol Sci       Date:  1999-09-29       Impact factor: 6.237

3.  Cleavage by granzyme B is strongly predictive of autoantigen status: implications for initiation of autoimmunity.

Authors:  L Casciola-Rosen; F Andrade; D Ulanet; W B Wong; A Rosen
Journal:  J Exp Med       Date:  1999-09-20       Impact factor: 14.307

Review 4.  Receptor-mediated control of regulatory volume decrease (RVD) and apoptotic volume decrease (AVD).

Authors:  Y Okada; E Maeno; T Shimizu; K Dezaki; J Wang; S Morishima
Journal:  J Physiol       Date:  2001-04-01       Impact factor: 5.182

5.  Akt/Protein kinase B inhibits cell death by preventing the release of cytochrome c from mitochondria.

Authors:  S G Kennedy; E S Kandel; T K Cross; N Hay
Journal:  Mol Cell Biol       Date:  1999-08       Impact factor: 4.272

Review 6.  Caspase inhibitors in prevention of apoptosis.

Authors:  T Rudel
Journal:  Herz       Date:  1999-05       Impact factor: 1.443

7.  NF-kappaB induces expression of the Bcl-2 homologue A1/Bfl-1 to preferentially suppress chemotherapy-induced apoptosis.

Authors:  C Y Wang; D C Guttridge; M W Mayo; A S Baldwin
Journal:  Mol Cell Biol       Date:  1999-09       Impact factor: 4.272

Review 8.  Higher levels of organization in the interphase nucleus of cycling and differentiated cells.

Authors:  A R Leitch
Journal:  Microbiol Mol Biol Rev       Date:  2000-03       Impact factor: 11.056

9.  Caspase-2 is localized at the Golgi complex and cleaves golgin-160 during apoptosis.

Authors:  M Mancini; C E Machamer; S Roy; D W Nicholson; N A Thornberry; L A Casciola-Rosen; A Rosen
Journal:  J Cell Biol       Date:  2000-05-01       Impact factor: 10.539

10.  Salmonella enterica serovars Typhimurium and Dublin can lyse macrophages by a mechanism distinct from apoptosis.

Authors:  P R Watson; A V Gautier; S M Paulin; A P Bland; P W Jones; T S Wallis
Journal:  Infect Immun       Date:  2000-06       Impact factor: 3.441
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