Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 The dynamics of cocirculating influenza strains conferring partial cross-immunity.

Literature DB >> 9269738

The dynamics of cocirculating influenza strains conferring partial cross-immunity.

Abstract

We develop a model that describes the dynamics of a finite number of strains that confer partial cross-protection among strains. The immunity structure of the host population is captured by an index-set notation where the index specifies the set of strains to which the host has been exposed. This notation allows us to derive threshold conditions for the invasion of a new strain and to show the existence of an endemic multi-strain equilibrium in a special case. The dynamics of systems consisting of more than two strains can exhibit sustained oscillations caused by an overshoot in the immunity to a specific strain of cross-protection is sufficiently strong.

Mesh：

Year: 1997 PMID： 9269738 DOI： 10.1007/s002850050079

Source DB: PubMed Journal: J Math Biol ISSN： 0303-6812 Impact factor: 2.259

Keyword Cloud
Cited

77 in total

1. On the determinants of population structure in antigenically diverse pathogens.

Authors: M Gabriela M Gomes; Graham F Medley; D James Nokes
Journal: Proc Biol Sci Date: 2002-02-07 Impact factor: 5.349

2. Dynamics and selection of many-strain pathogens.

Authors: Julia R Gog; Bryan T Grenfell
Journal: Proc Natl Acad Sci U S A Date: 2002-12-12 Impact factor: 11.205

3. The effects of host contact network structure on pathogen diversity and strain structure.

Authors: Caroline O'F Buckee; Katia Koelle; Matthew J Mustard; Sunetra Gupta
Journal: Proc Natl Acad Sci U S A Date: 2004-07-09 Impact factor: 11.205

4. Modeling rotavirus strain dynamics in developed countries to understand the potential impact of vaccination on genotype distributions.

Authors: Virginia E Pitzer; Manish M Patel; Ben A Lopman; Cécile Viboud; Umesh D Parashar; Bryan T Grenfell
Journal: Proc Natl Acad Sci U S A Date: 2011-11-14 Impact factor: 11.205

5. A two-tiered model for simulating the ecological and evolutionary dynamics of rapidly evolving viruses, with an application to influenza.

Authors: Katia Koelle; Priya Khatri; Meredith Kamradt; Thomas B Kepler
Journal: J R Soc Interface Date: 2010-03-24 Impact factor: 4.118

The dynamics of cocirculating influenza strains conferring partial cross-immunity.

1. On the determinants of population structure in antigenically diverse pathogens.

2. Dynamics and selection of many-strain pathogens.

3. The effects of host contact network structure on pathogen diversity and strain structure.

4. Modeling rotavirus strain dynamics in developed countries to understand the potential impact of vaccination on genotype distributions.

5. A two-tiered model for simulating the ecological and evolutionary dynamics of rapidly evolving viruses, with an application to influenza.

6. The effects of a deleterious mutation load on patterns of influenza A/H3N2's antigenic evolution in humans.

7. From within-host interactions to epidemiological competition: a general model for multiple infections.

8. Characterizing the symmetric equilibrium of multi-strain host-pathogen systems in the presence of cross immunity.

9. Dynamic effects of antibody-dependent enhancement on the fitness of viruses.

10. The impact of cross-immunity, mutation and stochastic extinction on pathogen diversity.