AIMS: To review vitamin D status and the relationship of serum 25-hydroxyvitamin D levels to hip bone mineral density in a group of healthy elderly women living independently in their own homes in Dunedin. METHODS: Thirty-eight elderly subjects (> 70 years of age) were studied. Serum levels of 25-hydroxyvitamin D (25(OH)D) were measured by radioimmunoassay in summer and winter. Femoral neck bone mineral density was measured by dual x-ray energy absorptiometry. RESULTS: Hip density was correlated with serum 25(OH)D levels at study entry. In summer, 10 of 38 patients (26.3%) had serum 25(OH)D levels below the reference range for healthy adults (40-185 nmol/L). Six patients subsequently withdrew from the study. In winter, 22 of the remaining 32 women (68.8%) had serum 25(OH)D values below the reference range. Subjects with low 25(OH)D values were given halibut oil tablets (400 IU vitamin D3 per day) to improve their serum 25(OH)D levels. CONCLUSIONS: Vitamin D deficiency is common among elderly women with a high risk of fracture who live in southern New Zealand. This is most marked in the winter months. Vitamin D replacement is cheap and effective and should be considered in patients over 70 years of age who have a high risk of fracture and who live in temperate climates.
AIMS: To review vitamin D status and the relationship of serum 25-hydroxyvitamin D levels to hip bone mineral density in a group of healthy elderly women living independently in their own homes in Dunedin. METHODS: Thirty-eight elderly subjects (> 70 years of age) were studied. Serum levels of 25-hydroxyvitamin D (25(OH)D) were measured by radioimmunoassay in summer and winter. Femoral neck bone mineral density was measured by dual x-ray energy absorptiometry. RESULTS: Hip density was correlated with serum 25(OH)D levels at study entry. In summer, 10 of 38 patients (26.3%) had serum 25(OH)D levels below the reference range for healthy adults (40-185 nmol/L). Six patients subsequently withdrew from the study. In winter, 22 of the remaining 32 women (68.8%) had serum 25(OH)D values below the reference range. Subjects with low 25(OH)D values were given halibut oil tablets (400 IU vitamin D3 per day) to improve their serum 25(OH)D levels. CONCLUSIONS:Vitamin D deficiency is common among elderly women with a high risk of fracture who live in southern New Zealand. This is most marked in the winter months. Vitamin D replacement is cheap and effective and should be considered in patients over 70 years of age who have a high risk of fracture and who live in temperate climates.
Authors: Z Petho; E Kulcsar-Jakab; E Kalina; A Balogh; A Pusztai; K Gulyas; A Horvath; Z Szekanecz; H P Bhattoa Journal: Osteoporos Int Date: 2015-02-19 Impact factor: 4.507
Authors: Jenny A Lucas; Mark J Bolland; Andrew B Grey; Ruth W Ames; Barbara H Mason; Anne M Horne; Greg D Gamble; Ian R Reid Journal: Osteoporos Int Date: 2005-07-19 Impact factor: 4.507
Authors: A Mithal; D A Wahl; J-P Bonjour; P Burckhardt; B Dawson-Hughes; J A Eisman; G El-Hajj Fuleihan; R G Josse; P Lips; J Morales-Torres Journal: Osteoporos Int Date: 2009-06-19 Impact factor: 4.507