Literature DB >> 926867

Aging in the nematode Caenorhabditis elegans: major biological and environmental factors influencing life span.

M R Klass.   

Abstract

The free-living nematode Caenorhabditis elegans is an excellent experimental system for the study of aging. The present study identifies some of the major biological and environmental factors influencing life span as a prelude to more detailed genetic and biochemical analyses. Life span can be altered during any part of the life cycle by a change in either temperature or food concentration. Parental age and parental life span both have relatively small effects on progeny life span. The nematode accumulates fluorescent pigment resembling lipofuscin, and becomes less sensitive to ultra-violet radiation as it ages.

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Year:  1977        PMID： 926867     DOI： 10.1016/0047-6374(77)90043-4

Source DB:  PubMed          Journal:  Mech Ageing Dev        ISSN： 0047-6374            Impact factor:   5.432


  234 in total

1.  Positive selection of Caenorhabditis elegans mutants with increased stress resistance and longevity.

Authors:  Manuel J Muñoz; Donald L Riddle
Journal:  Genetics       Date:  2003-01       Impact factor: 4.562

2.  Characterization of low molecular weight chemical fractions of dry bean (Phaseolus vulgaris) for bioactivity using Caenorhabditis elegans longevity and metabolite fingerprinting.

Authors:  Meghan M Mensack; Vanessa K Fitzgerald; Matthew R Lewis; Henry J Thompson
Journal:  J Agric Food Chem       Date:  2010-06-09       Impact factor: 5.279

3.  Measurements of age-related changes of physiological processes that predict lifespan of Caenorhabditis elegans.

Authors:  Cheng Huang; Chengjie Xiong; Kerry Kornfeld
Journal:  Proc Natl Acad Sci U S A       Date:  2004-05-12       Impact factor: 11.205

4.  Expression of a single-copy hsp-16.2 reporter predicts life span.

Authors:  Alexander R Mendenhall; Patricia M Tedesco; Larry D Taylor; Anita Lowe; James R Cypser; Thomas E Johnson
Journal:  J Gerontol A Biol Sci Med Sci       Date:  2012-01-06       Impact factor: 6.053

5.  The H3K27 demethylase UTX-1 regulates C. elegans lifespan in a germline-independent, insulin-dependent manner.

Authors:  Travis J Maures; Eric L Greer; Anna G Hauswirth; Anne Brunet
Journal:  Aging Cell       Date:  2011-09-16       Impact factor: 9.304

6.  Degeneracy and neuromodulation among thermosensory neurons contribute to robust thermosensory behaviors in Caenorhabditis elegans.

Authors:  Matthew Beverly; Sriram Anbil; Piali Sengupta
Journal:  J Neurosci       Date:  2011-08-10       Impact factor: 6.167

Review 7.  The extraordinary AFD thermosensor of C. elegans.

Authors:  Miriam B Goodman; Piali Sengupta
Journal:  Pflugers Arch       Date:  2017-12-08       Impact factor: 3.657

8.  Caenorhabditis Sieve: A Low-tech Instrument and Methodology for Sorting Small Multicellular Organisms.

Authors:  Skyler Hunter; Malabika Maulik; Courtney Scerbak; Elena Vayndorf; Barbara E Taylor
Journal:  J Vis Exp       Date:  2018-07-04       Impact factor: 1.355

Review 9.  P62/SQSTM1 at the interface of aging, autophagy, and disease.

Authors:  Alessandro Bitto; Chad A Lerner; Timothy Nacarelli; Elizabeth Crowe; Claudio Torres; Christian Sell
Journal:  Age (Dordr)       Date:  2014-02-21

10.  Automated high-content phenotyping from the first larval stage till the onset of adulthood of the nematode Caenorhabditis elegans.

Authors:  Huseyin Baris Atakan; Matteo Cornaglia; Laurent Mouchiroud; Johan Auwerx; Martin A M Gijs
Journal:  Lab Chip       Date:  2018-12-18       Impact factor: 6.799
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