Literature DB >> 9268013

A novel method for improving Streptomyces coelicolor A3(2) for production of actinorhodin by introduction of rpsL (encoding ribosomal protein S12) mutations conferring resistance to streptomycin.

A Hesketh, K Ochi.   

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Year:  1997        PMID: 9268013     DOI: 10.7164/antibiotics.50.532

Source DB:  PubMed          Journal:  J Antibiot (Tokyo)        ISSN: 0021-8820            Impact factor:   2.649


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  20 in total

1.  Novel approach for improving the productivity of antibiotic-producing strains by inducing combined resistant mutations.

Authors:  H Hu; K Ochi
Journal:  Appl Environ Microbiol       Date:  2001-04       Impact factor: 4.792

2.  The novel mutation K87E in ribosomal protein S12 enhances protein synthesis activity during the late growth phase in Escherichia coli.

Authors:  T Hosaka; N Tamehiro; N Chumpolkulwong; C Hori-Takemoto; M Shirouzu; S Yokoyama; K Ochi
Journal:  Mol Genet Genomics       Date:  2004-02-14       Impact factor: 3.291

3.  Improvement of alpha-amylase production by modulation of ribosomal component protein S12 in Bacillus subtilis 168.

Authors:  Kazuhiko Kurosawa; Takeshi Hosaka; Norimasa Tamehiro; Takashi Inaoka; Kozo Ochi
Journal:  Appl Environ Microbiol       Date:  2006-01       Impact factor: 4.792

4.  A novel insertion mutation in Streptomyces coelicolor ribosomal S12 protein results in paromomycin resistance and antibiotic overproduction.

Authors:  Guojun Wang; Takashi Inaoka; Susumu Okamoto; Kozo Ochi
Journal:  Antimicrob Agents Chemother       Date:  2008-12-22       Impact factor: 5.191

Review 5.  Insights into microbial cryptic gene activation and strain improvement: principle, application and technical aspects.

Authors:  Kozo Ochi
Journal:  J Antibiot (Tokyo)       Date:  2016-07-06       Impact factor: 2.649

6.  Mutations in rsmG, encoding a 16S rRNA methyltransferase, result in low-level streptomycin resistance and antibiotic overproduction in Streptomyces coelicolor A3(2).

Authors:  Kenji Nishimura; Takeshi Hosaka; Shinji Tokuyama; Susumu Okamoto; Kozo Ochi
Journal:  J Bacteriol       Date:  2007-03-23       Impact factor: 3.490

7.  Development of antibiotic-overproducing strains by site-directed mutagenesis of the rpsL gene in Streptomyces lividans.

Authors:  Yoshiko Okamoto-Hosoya; Susumu Okamoto; Kozo Ochi
Journal:  Appl Environ Microbiol       Date:  2003-07       Impact factor: 4.792

8.  Acquisition of certain streptomycin-resistant (str) mutations enhances antibiotic production in bacteria.

Authors:  Y Hosoya; S Okamoto; H Muramatsu; K Ochi
Journal:  Antimicrob Agents Chemother       Date:  1998-08       Impact factor: 5.191

9.  Enhanced expression of S-adenosylmethionine synthetase causes overproduction of actinorhodin in Streptomyces coelicolor A3(2).

Authors:  Susumu Okamoto; Alexander Lezhava; Takeshi Hosaka; Yoshiko Okamoto-Hosoya; Kozo Ochi
Journal:  J Bacteriol       Date:  2003-01       Impact factor: 3.490

10.  Innovative approach for improvement of an antibiotic-overproducing industrial strain of Streptomyces albus.

Authors:  Norimasa Tamehiro; Takeshi Hosaka; Jun Xu; Haifeng Hu; Noboru Otake; Kozo Ochi
Journal:  Appl Environ Microbiol       Date:  2003-11       Impact factor: 4.792

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