| Literature DB >> 92676 |
J A Eisman, T J Martin, I MacIntyre, J M Moseley.
Abstract
A specific receptor for 1,25-dihydroxyvitamin D has been demonstrated in a cultured human breast cancer cell line. This is the first such demonstration in any cancer cell. It may explain the high incidence of metastatic bone destruction and hypercalcaemia in this common malignancy, and the limited success of other steroid-receptor assays in predicting the response of breast cancer to therapy.Entities:
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Year: 1979 PMID： 92676 DOI： 10.1016/s0140-6736(79)92816-2
Source DB: PubMed Journal: Lancet ISSN： 0140-6736 Impact factor: 79.321