Literature DB >> 9267138

[MR imaging appearances of schwannoma: correlation with pathological findings].

Y Baba1, K Ohkubo, N Seino, H Churei, H Shirahama, M Nakajo.   

Abstract

Peripheral schwannomas are nerve sheath neoplasms that consist of focal proliferation of Schwann cells. We reviewed the MRI findings in 17 patients with pathologically proved peripheral schwannomas. When compared with the signal intensity of muscle, that of the mass was isointense or hyperintense on T1-weighted images and hyperintense in all 17 tumors on T2-weighted images. All of the masses showed heterogeneous enhancement following the intravenous injection of Gd-DTPA on T1-weighted images. On T1-weighted images, hyperintensity was observed in the tumors that contained predominantly hypercellular Antoni type A tissue, while isointensity was observed in the tumors that contained predominantly hypocellular Antoni type B tissue. Relatively high signal intensity seen on T2-weighted images and Gd-DTPA enhanced T1-weighted images was observed in the tumors that contained predominantly Antoni type B tissue when compared with the signal intensity of tumors that contained predominantly Antoni type A tissue. A capsule was pathologically identified in 15 of 17 tumors. MRI correctly identified the presence of a capsule in 11 of 15 tumors and the absence of a capsule in one of 2 tumors. Thus the diagnostic accuracy was 71% (12/17). The cause of 4 false negative results appeared to be a hemorrhage or cystic change around the peripheral portion of the tumor, and it appeared to be a chemical artifact in one false positive result. Thus the appearance of MRI may suggest the cellular type of schwannoma, Antoni type A or B. However, prediction of the presence or absence of tumor capsule may be relatively difficult with MRI.

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Year:  1997        PMID: 9267138

Source DB:  PubMed          Journal:  Nihon Igaku Hoshasen Gakkai Zasshi        ISSN: 0048-0428


  2 in total

1.  Intraosseous Schwannoma of the Petrous Apex.

Authors:  Ryota Tamura; Satoshi Takahashi; Maya Kohno; Kaori Kameyama; Hirokazu Fujiwara; Kazunari Yoshida
Journal:  J Neurol Surg Rep       Date:  2015-05-08

Review 2.  Disorders of neural crest derivates in oncoradiological practice.

Authors:  Tamas Papp; Zsuzsanna Ferenczi; Matyas Petro; Zoltan Meszar; Zita Kepes; Ervin Berenyi
Journal:  Transl Cancer Res       Date:  2019-12       Impact factor: 1.241

  2 in total

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