| Literature DB >> 9266949 |
I Kubonishi1, K Bandobashi, N Murata, M Daibata, E Ido, H Sonobe, Y Ohtsuki, I Miyoshi.
Abstract
We report a 53-year-old-man with an aggressive Ki-1 lymphoma who had high serum CA125, a marker protein of the epithelial ovarian cancer, and interleukin-6 (IL-6) concentrations. Both CA125 and IL-6 levels decreased after chemotherapy and elevated with disease progression. The patient's lymphoma cells obtained before chemotherapy grew continuously in vitro, were IL-6 dependent and were found to secrete CA125 in culture medium. These results indicate that CA125 can be secreted by Ki-1 lymphoma cells and IL-6 may promote the growth of Ki-1 lymphoma cells.Entities:
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Year: 1997 PMID： 9266949 DOI： 10.1046/j.1365-2141.1997.2383054.x
Source DB: PubMed Journal: Br J Haematol ISSN： 0007-1048 Impact factor: 6.998