Literature DB >> 9266537

Coenzyme Q homologs and vitamin E in synaptic and non-synaptic occipital cerebral cortex mitochondria in the ageing rat.

M Battino1, S Svegliati Baroni, G P Littarru, S Bompadre, L Leone, A Gorini, R F Villa.   

Abstract

The coenzyme Q8 (CoQ8) and alpha-tocopherol contents of different mitochondrial fractions were investigated from occipital cerebral cortices of different ages. The highest CoQ8 and vitamin E concentrations were found in non-synaptic free mitochondria (FM) fractions. In several cases heavy mitochondria (HM) fractions displayed the lowest values. Occipital cerebral cortex mitochondria contained higher CoQ9 and lower CoQ10 amounts than those typical for other brain regions.

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Year:  1997        PMID: 9266537     DOI: 10.1016/s0098-2997(97)00023-x

Source DB:  PubMed          Journal:  Mol Aspects Med        ISSN: 0098-2997


  1 in total

1.  Cerebral cortex synaptic heavy mitochondria may represent the oldest synaptic mitochondrial population: biochemical heterogeneity and effects of L-acetylcarnitine.

Authors:  M Battino; J L Quiles; J R Huertas; J F Mataix; R F Villa; A Gorini
Journal:  J Bioenerg Biomembr       Date:  2000-04       Impact factor: 2.945

  1 in total

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