Literature DB >> 9266365

Valproate inhibits the mitochondrial pyruvate-driven oxidative phosphorylation in vitro.

M F Silva1, J P Ruiter, L Illst, C Jakobs, M Duran, I T de Almeida, R J Wanders.   

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Year:  1997        PMID： 9266365     DOI： 10.1023/a:1005398516208

Source DB:  PubMed          Journal:  J Inherit Metab Dis        ISSN： 0141-8955            Impact factor:   4.982


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  7 in total

1.  In vitro effects of eight-carbon fatty acids on oxidations in rat liver mitochondria.

Authors:  K Veitch; F Van Hoof
Journal:  Biochem Pharmacol       Date:  1990-11-01       Impact factor: 5.858

2.  In vitro effects of valproate and valproate metabolites on mitochondrial oxidations. Relevance of CoA sequestration to the observed inhibitions.

Authors:  S Ponchaut; F van Hoof; K Veitch
Journal:  Biochem Pharmacol       Date:  1992-06-09       Impact factor: 5.858

3.  Inhibition of oxidative phosphorylation in hepatic and cerebral mitochondria of sodium valproate-treated rats.

Authors:  L Rumbach; J M Warter; A Rendon; C Marescaux; G Micheletti; A Waksman
Journal:  J Neurol Sci       Date:  1983 Oct-Nov       Impact factor: 3.181

4.  Inhibitory effects of sodium valproate on oxidative phosphorylation.

Authors:  R Haas; D A Stumpf; J K Parks; L Eguren
Journal:  Neurology       Date:  1981-11       Impact factor: 9.910

5.  Studies on mitochondrial oxidative phosphorylation in permeabilized human skin fibroblasts: application to mitochondrial encephalomyopathies.

Authors:  R J Wanders; J P Ruiter; F A Wijburg
Journal:  Biochim Biophys Acta       Date:  1993-06-19

Review 6.  Metabolism of valproate to hepatotoxic intermediates.

Authors:  T A Baillie
Journal:  Pharm Weekbl Sci       Date:  1992-06-19

7.  Influence of valproic acid on hepatic carbohydrate and lipid metabolism.

Authors:  C M Becker; R A Harris
Journal:  Arch Biochem Biophys       Date:  1983-06       Impact factor: 4.013
  7 in total
  8 in total

Review 1.  Mechanisms of drug-induced liver injury: from bedside to bench.

Authors:  Shannan Tujios; Robert J Fontana
Journal:  Nat Rev Gastroenterol Hepatol       Date:  2011-03-08       Impact factor: 46.802

Review 2.  Dihydrolipoamide dehydrogenase, pyruvate oxidation, and acetylation-dependent mechanisms intersecting drug iatrogenesis.

Authors:  I F Duarte; J Caio; M F Moedas; L A Rodrigues; A P Leandro; I A Rivera; M F B Silva
Journal:  Cell Mol Life Sci       Date:  2021-10-31       Impact factor: 9.261

Review 3.  SARS-CoV-2 Infection, Sex-Related Differences, and a Possible Personalized Treatment Approach with Valproic Acid: A Review.

Authors:  Donatas Stakišaitis; Linas Kapočius; Angelija Valančiūtė; Ingrida Balnytė; Tomas Tamošuitis; Arūnas Vaitkevičius; Kęstutis Sužiedėlis; Daiva Urbonienė; Vacis Tatarūnas; Evelina Kilimaitė; Dovydas Gečys; Vaiva Lesauskaitė
Journal:  Biomedicines       Date:  2022-04-21

4.  Cross-talk between neurons and astrocytes in response to bilirubin: early beneficial effects.

Authors:  Ana Sofia Falcão; Rui F M Silva; Ana Rita Vaz; Sandra Leitão Silva; Adelaide Fernandes; Dora Brites
Journal:  Neurochem Res       Date:  2013-01-03       Impact factor: 3.996

5.  Effects of valproic acid on organic acid metabolism in children: a metabolic profiling study.

Authors:  K E Price; R E Pearce; U C Garg; B A Heese; L D Smith; J E Sullivan; M J Kennedy; J F Bale; R M Ward; T K H Chang; F S Abbott; J S Leeder
Journal:  Clin Pharmacol Ther       Date:  2011-05-04       Impact factor: 6.875

6.  Mitochondrial Liver Toxicity of Valproic Acid and Its Acid Derivatives Is Related to Inhibition of α-Lipoamide Dehydrogenase.

Authors:  Alexei P Kudin; Hafiz Mawasi; Arik Eisenkraft; Christian E Elger; Meir Bialer; Wolfram S Kunz
Journal:  Int J Mol Sci       Date:  2017-09-06       Impact factor: 5.923

Review 7.  Impact of pharmacological agents on mitochondrial function: a growing opportunity?

Authors:  Megan L Stoker; Emma Newport; James C Hulit; A Phillip West; Karl J Morten
Journal:  Biochem Soc Trans       Date:  2019-12-20       Impact factor: 5.407

Review 8.  The Role of Mitochondria in Mood Disorders: From Physiology to Pathophysiology and to Treatment.

Authors:  Anna Giménez-Palomo; Seetal Dodd; Gerard Anmella; Andre F Carvalho; Giselli Scaini; Joao Quevedo; Isabella Pacchiarotti; Eduard Vieta; Michael Berk
Journal:  Front Psychiatry       Date:  2021-07-06       Impact factor: 4.157
  8 in total

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