Literature DB >> 9266176

Helix packing in polytopic membrane proteins: the lactose permease of Escherichia coli.

H R Kaback1, J Voss, J Wu.   

Abstract

Recent advances in protein engineering have facilitated the development of alternative approaches to determine helix packing in polytopic membrane proteins. Using the lac permease as a paradigm, several site-directed biophysical and biochemical techniques are described which should be generally applicable.

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Year:  1997        PMID： 9266176     DOI： 10.1016/s0959-440x(97)80119-4

Source DB:  PubMed          Journal:  Curr Opin Struct Biol        ISSN： 0959-440X            Impact factor:   6.809


  17 in total

1.  Conformational flexibility at the substrate binding site in the lactose permease of Escherichia coli.

Authors:  A B Weinglass; H R Kaback
Journal:  Proc Natl Acad Sci U S A       Date:  1999-09-28       Impact factor: 11.205

Review 2.  A functional-phylogenetic classification system for transmembrane solute transporters.

Authors:  M H Saier
Journal:  Microbiol Mol Biol Rev       Date:  2000-06       Impact factor: 11.056

3.  The central cytoplasmic loop of the major facilitator superfamily of transport proteins governs efficient membrane insertion.

Authors:  A B Weinglass; H R Kaback
Journal:  Proc Natl Acad Sci U S A       Date:  2000-08-01       Impact factor: 11.205

Review 4.  Vectorial metabolism and the evolution of transport systems.

Authors:  M H Saier
Journal:  J Bacteriol       Date:  2000-09       Impact factor: 3.490

5.  Topological changes in the transmembrane domains of hepatitis C virus envelope glycoproteins.

Authors:  Laurence Cocquerel; Anne Op de Beeck; Michel Lambot; Juliette Roussel; David Delgrange; André Pillez; Czeslaw Wychowski; François Penin; Jean Dubuisson
Journal:  EMBO J       Date:  2002-06-17       Impact factor: 11.598

6.  Mutational analysis of trans-membrane helices M3, M4, M5 and M7 of the fast-twitch Ca2+-ATPase.

Authors:  P Adams; J M East; A G Lee; C D O'Connor
Journal:  Biochem J       Date:  1998-10-01       Impact factor: 3.857

7.  Towards a new age of virtual ADME/TOX and multidimensional drug discovery.

Authors:  Sean Ekins; Bruno Boulanger; Peter W Swaan; Maggie A Z Hupcey
Journal:  J Comput Aided Mol Des       Date:  2002 May-Jun       Impact factor: 3.686

8.  The lipid bilayer determines helical tilt angle and function in lactose permease of Escherichia coli.

Authors:  J le Coutre; L R Narasimhan; C K Patel; H R Kaback
Journal:  Proc Natl Acad Sci U S A       Date:  1997-09-16       Impact factor: 11.205

9.  The substrate-binding site in the lactose permease of Escherichia coli.

Authors:  P Venkatesan; H R Kaback
Journal:  Proc Natl Acad Sci U S A       Date:  1998-08-18       Impact factor: 11.205

10.  Identification of essential charged residues in transmembrane segments of the multidrug transporter MexB of Pseudomonas aeruginosa.

Authors:  L Guan; T Nakae
Journal:  J Bacteriol       Date:  2001-03       Impact factor: 3.490
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