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Literature DB >> 9266153

Apoptosis in neurodegenerative disorders.

Abstract

We review here recent reports pertaining to the issue of apoptosis in neurodegenerative diseases. Tissue culture models, animal models and human pathological studies are discussed. At present, there is supportive, but not definitive, evidence for apoptosis in a number of neurodegenerative disorders.

Entities: Disease Species

Mesh：

Year: 1997 PMID： 9266153 DOI： 10.1097/00019052-199708000-00004

Source DB: PubMed Journal: Curr Opin Neurol ISSN： 1350-7540 Impact factor: 5.710

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Cited

24 in total

1. Cyclin-dependent kinases and P53 pathways are activated independently and mediate Bax activation in neurons after DNA damage.

Authors: E J Morris; E Keramaris; H J Rideout; R S Slack; N J Dyson; L Stefanis; D S Park
Journal: J Neurosci Date: 2001-07-15 Impact factor: 6.167

2. Transgenic mice with SCA10 pentanucleotide repeats show motor phenotype and susceptibility to seizure: a toxic RNA gain-of-function model.

Authors: Misti White; Guangbin Xia; Rui Gao; Maki Wakamiya; Partha S Sarkar; Karen McFarland; Tetsuo Ashizawa
Journal: J Neurosci Res Date: 2011-11-08 Impact factor: 4.164

3. Neuroprotection of atractylenolide III from Atractylodis macrocephalae against glutamate-induced neuronal apoptosis via inhibiting caspase signaling pathway.

Authors: Chao Liu; Hong Zhao; Zhi-Hong Ji; Xin-Yu Yu
Journal: Neurochem Res Date: 2014-06-24 Impact factor: 3.996

4. Regulation and localization of tyrosine216 phosphorylation of glycogen synthase kinase-3beta in cellular and animal models of neuronal degeneration.

Authors: R V Bhat; J Shanley; M P Correll; W E Fieles; R A Keith; C W Scott; C M Lee
Journal: Proc Natl Acad Sci U S A Date: 2000-09-26 Impact factor: 11.205

10. Cyclin dependent kinase inhibitors and dominant negative cyclin dependent kinase 4 and 6 promote survival of NGF-deprived sympathetic neurons.

Authors: D S Park; B Levine; G Ferrari; L A Greene
Journal: J Neurosci Date: 1997-12-01 Impact factor: 6.167

Apoptosis in neurodegenerative disorders.

1. Cyclin-dependent kinases and P53 pathways are activated independently and mediate Bax activation in neurons after DNA damage.

2. Transgenic mice with SCA10 pentanucleotide repeats show motor phenotype and susceptibility to seizure: a toxic RNA gain-of-function model.

3. Neuroprotection of atractylenolide III from Atractylodis macrocephalae against glutamate-induced neuronal apoptosis via inhibiting caspase signaling pathway.

4. Regulation and localization of tyrosine216 phosphorylation of glycogen synthase kinase-3beta in cellular and animal models of neuronal degeneration.

5. Involvement of retinoblastoma family members and E2F/DP complexes in the death of neurons evoked by DNA damage.

6. c-fos controls the "private pathway" of light-induced apoptosis of retinal photoreceptors.

7. The Chk1/Cdc25A pathway as activators of the cell cycle in neuronal death induced by camptothecin.

8. Caspases 3 and 9 send a pro-apoptotic signal from synapse to cell body in olfactory receptor neurons.

9. Role of glycogen synthase kinase-3beta in neuronal apoptosis induced by trophic withdrawal.

10. Cyclin dependent kinase inhibitors and dominant negative cyclin dependent kinase 4 and 6 promote survival of NGF-deprived sympathetic neurons.