Literature DB >> 9263634

Killing two birds with one stone: a chemically plausible scheme for linked nucleic acid replication and coded peptide synthesis.

J D Sutherland1, J M Blackburn.   

Abstract

To understand how life began, we must explain the origins of nucleic acid replication and genetically coded peptide synthesis. Neither of these is easy to explain individually; here, we propose a chemically plausible scheme for the evolution of a process that simultaneously produced both polymers. Later, two separate machineries could have evolved from the linked process.

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Year:  1997        PMID: 9263634     DOI: 10.1016/s1074-5521(97)90318-5

Source DB:  PubMed          Journal:  Chem Biol        ISSN: 1074-5521


  4 in total

1.  Templates direct the sequence-specific anchoring of the C-terminus of peptido RNAs.

Authors:  Biswarup Jash; Clemens Richert
Journal:  Chem Sci       Date:  2020-03-02       Impact factor: 9.825

2.  Spontaneous Formation of RNA Strands, Peptidyl RNA, and Cofactors.

Authors:  Mario Jauker; Helmut Griesser; Clemens Richert
Journal:  Angew Chem Int Ed Engl       Date:  2015-10-05       Impact factor: 15.336

3.  Direct interplay between stereochemistry and conformational preferences in aminoacylated oligoribonucleotides.

Authors:  Anton A Polyansky; Mathias Kreuter; John D Sutherland; Bojan Zagrovic
Journal:  Nucleic Acids Res       Date:  2019-12-02       Impact factor: 16.971

4.  Physicochemical Foundations of Life that Direct Evolution: Chance and Natural Selection are not Evolutionary Driving Forces.

Authors:  Didier Auboeuf
Journal:  Life (Basel)       Date:  2020-01-21
  4 in total

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