Literature DB >> 92625

Sensitive trypsin assay for dried-blood specimens as a screening procedure for early detection of cystic fibrosis.

D N King, A F Heeley, M P Walsh, J A Kuzemko.   

Abstract

An immunoreactive-trypsin assay uses small dried-blood spots (diameter 1.25 mm) and is therefore suitable for incorporation in established neonatal screening schemes. Blood specimens from neonates with cystic fibrosis had trypsin levels greater than those in control subjects, thus confirming earlier findings. Trypsin levels were below normal in several older patients with cystic fibrosis.

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Year:  1979        PMID： 92625     DOI： 10.1016/s0140-6736(79)92336-5

Source DB:  PubMed          Journal:  Lancet        ISSN： 0140-6736            Impact factor:   79.321


  12 in total

1.  Variations in dried blood spot immunoreactive trypsin in relation to gestational age and during the first week of life.

Authors:  J P Bourguignon; G Deby-Dupont; A Reuter; J Senterre; A Gérard; P Franchimont
Journal:  Eur J Pediatr       Date:  1986-04       Impact factor: 3.183

Review 2.  Screening, early neonatal diagnosis and prenatal diagnosis.

Authors:  J A Kuzemko
Journal:  J R Soc Med       Date:  1986       Impact factor: 5.344

Review 3.  Laboratory tests in the diagnosis of the chronic pancreatic diseases. Part 4. Tests involving the measurement of pancreatic enzymes in body fluid.

Authors:  E J Boyd; H Rinderknecht; K G Wormsley
Journal:  Int J Pancreatol       Date:  1988 Jan-Feb

4.  Screening for cystic fibrosis by died blood spot trypsin assay.

Authors:  A F Heeley; M E Heeley; D N King; J A Kuzemko; M P Walsh
Journal:  Arch Dis Child       Date:  1982-01       Impact factor: 3.791

5.  Serum immuno reactive trypsin and pancreatic isoamylase in older patients with cystic fibrosis.

Authors:  M J Tobin; M J Duffy; G Duffy; M X FitzGerald
Journal:  Ir J Med Sci       Date:  1981-11       Impact factor: 1.568

6.  Satisfactory screening for cystic fibrosis with the BM meconium procedure.

Authors:  R T Evans; A J Little; A E Steel; J M Littlewood
Journal:  J Clin Pathol       Date:  1981-08       Impact factor: 3.411

7.  Neonatal screening strategy for cystic fibrosis using immunoreactive trypsinogen and direct gene analysis.

Authors:  E Ranieri; R G Ryall; C P Morris; P V Nelson; W F Carey; A C Pollard; E F Robertson
Journal:  BMJ       Date:  1991-05-25

8.  Comparison of the diagnostic value of serum pancreatic isoamylase and immunoreactive trypsin measurement in patients with cystic fibrosis.

Authors:  R C Brown; D M Chalmers; V L Rowe; J Kelleher; J M Littlewood; M S Losowsky
Journal:  J Clin Pathol       Date:  1982-05       Impact factor: 3.411

9.  Immunoreactive trypsin levels in young cystic fibrosis patients and in other sick children.

Authors:  F M Hallinan; E Tempany
Journal:  Ir J Med Sci       Date:  1983-11       Impact factor: 1.568

10.  Secretin pancreozymin stimulation test and confirmation of the diagnosis of cystic fibrosis.

Authors:  L T Wong; S Turtle; A G Davidson
Journal:  Gut       Date:  1982-09       Impact factor: 23.059
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