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Literature DB >> 926134

G gamma delta beta thalassaemia and g gamma HPFH (Hb Kenya type): comparison of 2 new cases.

W G Wood, J B Clegg, D J Weatherall, O H Gyde, D A Obeid, M J Tarlow, M J Brown, S Hewitt.

Abstract

Two new cases of G gamma delta beta thalassaemia and G gamma HPFH (Hb Kenya type) have been characterised in detail and compared with regard to haematological data, globin chains biosynthesis, and intracellular distribution of Hb F. The similarities and differences between these two conditions are discussed in relation to the possible underlying defects at the molecular level and to the control of the gamma delta beta gene complex in general.

Entities: Disease

Mesh：

Substances：

Year: 1977 PMID： 926134 PMCID： PMC1013575 DOI： 10.1136/jmg.14.4.237

Source DB: PubMed Journal: J Med Genet ISSN： 0022-2593 Impact factor: 6.318

34 in total

1. BIOCHEMICAL PHENOTYPES OF THALASSEMIA IN THE AMERICAN NEGRO POPULATION.

Authors: D J WEATHERALL
Journal: Ann N Y Acad Sci Date: 1964-10-07 Impact factor: 5.691

2. Hereditary persistence of fetal hemoglobin: a study of 79 affected persons in 15 Negro families in Baltimore.

Authors: C L CONLEY; D J WEATHERALL; S N RICHARDSON; M K SHEPARD; S CHARACHE
Journal: Blood Date: 1963-03 Impact factor: 22.113

3. The homozygous state of persistent fetal hemoglobin and the interaction of persistent fetal hemoglobin with thalassemia.

Authors: J T WHEELER; J R KREVANS
Journal: Bull Johns Hopkins Hosp Date: 1961-11

G gamma delta beta thalassaemia and g gamma HPFH (Hb Kenya type): comparison of 2 new cases.

1. BIOCHEMICAL PHENOTYPES OF THALASSEMIA IN THE AMERICAN NEGRO POPULATION.

2. Hereditary persistence of fetal hemoglobin: a study of 79 affected persons in 15 Negro families in Baltimore.

3. The homozygous state of persistent fetal hemoglobin and the interaction of persistent fetal hemoglobin with thalassemia.

4. [Photometric evaluation of non-transparent paper-electropherograms].

5. The Negro variety of hereditary persistence of fetal haemoglobin is a mild form of thalassaemia.

6. Balanced globin chain synthesis in hereditary persistence of fetal hemoglobin.

7. Beta-thalassemia in the American Negro.

8. The synthesis of human haemoglobin A 2 during erythroid maturation.

9. The pattern of disordered haemoglobin synthesis in homozygous and heterozygous beta-thalassaemia.

10. Delta-beta-thalassemia is due to a gene deletion.

1. Interaction of alpha- and delta beta o- thalassaemia: haematological features and globin chain synthesis analysis.

2. G gamma beta + type of hereditary persistence of fetal haemoglobin in association with Hb C.

3. Delta beta (F)-thalassaemia in Sardinia.