| Literature DB >> 9261054 |
Abstract
ATP-sensitive potassium channels, KATP channels are critical for the normal regulation of insulin secretion. The cloning of cDNAs encoding the subunits of these channels shows that they are a novel combination of an ATP-binding protein and a small inward rectifier. Loss of pancreatic beta-cell KATP channels has been shown to cause familial hyperinsulinism.Entities:
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Year: 1997 PMID: 9261054 DOI: 10.1016/s0955-0674(97)80033-6
Source DB: PubMed Journal: Curr Opin Cell Biol ISSN: 0955-0674 Impact factor: 8.382