Literature DB >> 9260728

Serotonin, dopamine, and motor effects in Parkinson's disease.

E Miyawaki1, Y Meah, W C Koller.   

Abstract

We review recent reports suggesting that use of selective serotonergic agents that either inhibit synaptic reuptake or have specific serotonin receptor affinities may benefit a variety of motor disturbances in Parkinson's disease. The complex, mixed motoric effects of these agents in Parkinson's disease have not allowed for a consistent view on the interrelationship between dopamine and serotonin (5HT) in motor control but may speak to the nature of dysregulated neurotransmission in the disease.

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Year:  1997        PMID: 9260728     DOI: 10.1097/00002826-199708000-00002

Source DB:  PubMed          Journal:  Clin Neuropharmacol        ISSN: 0362-5664            Impact factor:   1.592


  5 in total

Review 1.  Pharmacological treatment of Parkinson's disease.

Authors:  A Münchau; K P Bhatia
Journal:  Postgrad Med J       Date:  2000-10       Impact factor: 2.401

Review 2.  Serotonergic mechanisms in Parkinson's disease: opposing results from preclinical and clinical data.

Authors:  B Scholtissen; F R J Verhey; H W M Steinbusch; A F G Leentjens
Journal:  J Neural Transm (Vienna)       Date:  2005-10-27       Impact factor: 3.575

3.  The role of anxiety in the development of levodopa-induced dyskinesias in an animal model of Parkinson's disease, and the effect of chronic treatment with the selective serotonin reuptake inhibitor citalopram.

Authors:  Wei-Li Kuan; Jing-Wei Zhao; Roger A Barker
Journal:  Psychopharmacology (Berl)       Date:  2007-12-23       Impact factor: 4.530

4.  The selective 5-HT1A receptor antagonist WAY-100635 inhibits neuronal activity of the ventromedial prefrontal cortex in a rodent model of Parkinson's disease.

Authors:  Jian Cao; Jian Liu; Qiao-Jun Zhang; Tao Wang; Shuang Wang; Ling-Na Han; Qiang Li
Journal:  Neurosci Bull       Date:  2007-11       Impact factor: 5.203

5.  Buspirone improves haloperidol-induced Parkinson disease in mice through 5-HT(1A) recaptors.

Authors:  A Mohajjel Nayebi A; H Sheidaei
Journal:  Daru       Date:  2010       Impact factor: 3.117

  5 in total

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