Alcohol use disorders and neuropsychological functioning in first-year undergraduates.

The relation between alcohol use disorders and neuropsychological functioning was examined in 489 first-year undergraduates, approximately half of whom had a history of alcoholism in their biological fathers. Factor analyses of 17 neuropsychological tests and subtests produced the following 5 factors that were the basis of subsequent analyses: Language/Verbal Memory, Visuospatial Ability, Motor Speed, Booklet Category Performance, and Attention. Participants with alcohol use disorders showed deficits in visuospatial ability. Those who had alcohol dependence showed deficits in both visuospatial ability and motor speed relative to participants who abused alcohol. The differences in neuropsychological functioning remained even after several potential confounding variables were controlled statistically. Results suggest that alcohol use disorders in first-year college students are associated with deficits in neuropsychological measures that are not attributable to several potential third-variable explanations.