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Literature DB >> 9258541

Molecular analysis of an outbreak of influenza in the United Kingdom.

Abstract

The first outbreak of influenza virus in Europe in 1995/1996 occurred in a school in the south of England. RT-PCR-restriction analysis was performed on the HA1 portion of influenza haemagglutinin gene amplified directly from clinical samples. These were taken at the onset of the outbreak and indicated co-circulation of two distinct genetic variants of influenza virus which were antigenically identical. Investigations of this nature demonstrate the genetic diversity of circulating variants of influenza and have the potential to provide information on molecular evolution of strains within closed populations.

Entities: Species

Mesh：

Year: 1997 PMID： 9258541 PMCID： PMC7088088 DOI： 10.1023/a:1007391222905

Source DB: PubMed Journal: Eur J Epidemiol ISSN： 0393-2990 Impact factor: 8.082

5 in total

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2. The neighbor-joining method: a new method for reconstructing phylogenetic trees.

Authors: N Saitou; M Nei
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Journal: Commun Dis Rep CDR Rev Date: 1995-12-08

4. Detection and identification of human influenza viruses by the polymerase chain reaction.

Authors: W D Zhang; D H Evans
Journal: J Virol Methods Date: 1991-06 Impact factor: 2.014

5. PCR restriction analysis of genome composition and stability of cold-adapted reassortant live influenza vaccines.

Authors: A I Klimov; N J Cox
Journal: J Virol Methods Date: 1995-03 Impact factor: 2.014

5 in total

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Authors: Y Natori; A Humar; J Lipton; D D Kim; P Ashton; K Hoschler; D Kumar
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3. Safety and immunogenicity of AS03B adjuvanted split virion versus non-adjuvanted whole virion H1N1 influenza vaccine in UK children aged 6 months-12 years: open label, randomised, parallel group, multicentre study.

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Journal: J Virol Date: 2006-05 Impact factor: 5.103

5. Detailed analysis of the genetic evolution of influenza virus during the course of an epidemic.

Authors: A Lavenu; M Leruez-Ville; M-L Chaix; P-Y Boelle; S Rogez; F Freymuth; A Hay; C Rouzioux; F Carrat
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6. Coadministration of seasonal influenza vaccine and MVA-NP+M1 simultaneously achieves potent humoral and cell-mediated responses.

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7. H1N1 antibody persistence 1 year after immunization with an adjuvanted or whole-virion pandemic vaccine and immunogenicity and reactogenicity of subsequent seasonal influenza vaccine: a multicenter follow-on study.

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8. Understanding the dynamics of seasonal influenza in Italy: incidence, transmissibility and population susceptibility in a 9-year period.

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9. Effect of a Russian-backbone live-attenuated influenza vaccine with an updated pandemic H1N1 strain on shedding and immunogenicity among children in The Gambia: an open-label, observational, phase 4 study.

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10. The effect of H1N1 vaccination on serum miRNA expression in children: A tale of caution for microRNA microarray studies.

Authors: Ruth Elizabeth Drury; Andrew John Pollard; Daniel O'Connor
Journal: PLoS One Date: 2019-08-20 Impact factor: 3.240