| Literature DB >> 925819 |
S McIntosh, D B Fischer, S G Rothman, N Rosenfield, J S Lobel, R O'Brien.
Abstract
Children with acute lymphocytic leukemia were examined for evidence of intracranial calcifications with roentgenograms of the skull and computerized tomography. Of 39 children in their initial complete remission, ten were found to have subcortical cerebral calcifications. Significant associations were found between the presence of cerebral calcifications and systemic treatment with large cumulative doses of methotrexate.Entities:
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Year: 1977 PMID： 925819 DOI： 10.1016/s0022-3476(77)80888-3
Source DB: PubMed Journal: J Pediatr ISSN： 0022-3476 Impact factor: 4.406