R W Grady1, J H Ross, R Kay. 1. Department of Urology, Cleveland Clinic Foundation, Ohio 44195, USA.
Abstract
PURPOSE: Prepubertal teratomas of the testis are rare benign tumors. Knowledge of the epidemiology of testicular teratomas and associated alpha-fetoprotein (AFP) levels could assist in planning treatment for prepubertal patients suspected of having teratoma of the testis. MATERIALS AND METHODS: We evaluated data on testicular teratoma from the Prepubertal Testis Tumor Registry of the Section on Urology of the American Academy of Pediatrics. RESULTS: Median patient age at presentation was 13 months. Teratomas occurred equally in the right and left testes. Most patients presented with a scrotal mass. Preoperative AFP levels were elevated in 20 of the 34 patients and postoperative levels were elevated in 9 of 10. Most patients were treated with radical orchiectomy and no metastatic disease was reported. CONCLUSIONS: Data in the registry confirm the benign nature of this tumor. Normal AFP levels should not be expected in infants with teratoma.
PURPOSE: Prepubertal teratomas of the testis are rare benign tumors. Knowledge of the epidemiology of testicular teratomas and associated alpha-fetoprotein (AFP) levels could assist in planning treatment for prepubertal patients suspected of having teratoma of the testis. MATERIALS AND METHODS: We evaluated data on testicular teratoma from the Prepubertal Testis Tumor Registry of the Section on Urology of the American Academy of Pediatrics. RESULTS: Median patient age at presentation was 13 months. Teratomas occurred equally in the right and left testes. Most patients presented with a scrotal mass. Preoperative AFP levels were elevated in 20 of the 34 patients and postoperative levels were elevated in 9 of 10. Most patients were treated with radical orchiectomy and no metastatic disease was reported. CONCLUSIONS: Data in the registry confirm the benign nature of this tumor. Normal AFP levels should not be expected in infants with teratoma.
Authors: Anna Lavinia Bulotta; Francesco Molinaro; Rossella Angotti; Francesco Ferrara; Giovanni Di Maggio; Edoardo Bindi; Mario Messina Journal: Ital J Pediatr Date: 2012-12-06 Impact factor: 2.638