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Literature DB >> 9257771

Enhancement of nitric oxide synthesis by macrophages represents an additional mechanism of action for amphotericin B.

N Mozaffarian¹, J W Berman, A Casadevall.

Abstract

Amphotericin B (AmB) enhanced nitrite synthesis by murine macrophage-like J774.16 cells in a dose-dependent fashion. This effect was retained in the presence of Cryptococcus neoformans capsular polysaccharide, a known virulence factor. AmB and anticapsular antibody increased nitrite synergistically. In all cases, AmB required gamma interferon; C. neoformans cells were unable to elicit nitrite, with or without AmB.

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Year: 1997 PMID： 9257771 PMCID： PMC164015

Source DB: PubMed Journal: Antimicrob Agents Chemother ISSN： 0066-4804 Impact factor: 5.191

53 in total

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Authors: M A GORDON; E LAPA
Journal: J Infect Dis Date: 1964-10 Impact factor: 5.226

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Journal: J Infect Dis Date: 1989-01 Impact factor: 5.226

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Journal: Hum Pathol Date: 1996-08 Impact factor: 3.466

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Journal: Infect Immun Date: 1991-10 Impact factor: 3.441

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Authors: S C Lee; A Casadevall; D W Dickson
Journal: Am J Pathol Date: 1996-04 Impact factor: 4.307

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Authors: D Goldman; Y Cho; M Zhao; A Casadevall; S C Lee
Journal: Am J Pathol Date: 1996-04 Impact factor: 4.307

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Authors: A Casadevall; J Mukherjee; M D Scharff
Journal: J Immunol Methods Date: 1992-09-18 Impact factor: 2.303

8. Immune complexes increase nitric oxide production by interferon-gamma- stimulated murine macrophage-like J774.16 cells.

Authors: N Mozaffarian; J W Berman; A Casadevall
Journal: J Leukoc Biol Date: 1995-04 Impact factor: 4.962

9. Nonencapsulated Variant of Cryptococcus neoformans I. Virulence Studies and Characterization of Soluble Polysaccharide.

Authors: T R Kozel; J Cazin
Journal: Infect Immun Date: 1971-02 Impact factor: 3.441

10. Downregulation by cryptococcal polysaccharide of tumor necrosis factor alpha and interleukin-1 beta secretion from human monocytes.

Authors: A Vecchiarelli; C Retini; D Pietrella; C Monari; C Tascini; T Beccari; T R Kozel
Journal: Infect Immun Date: 1995-08 Impact factor: 3.441

14 in total

Review 1. Mechanisms of resistance to oxidative and nitrosative stress: implications for fungal survival in mammalian hosts.

Authors: Tricia A Missall; Jennifer K Lodge; Joan E McEwen
Journal: Eukaryot Cell Date: 2004-08

Review 2. Immune response and immunotherapy to Cryptococcus infections.

Authors: Qing Zhou; William J Murphy
Journal: Immunol Res Date: 2006 Impact factor: 2.829

3. Reduction of no synthase expression and tumor necrosis factor alpha production in macrophages by amphotericin B lipid carriers.

Authors: M Larabi; P Legrand; M Appel; S Gil; M Lepoivre; J Devissaguet; F Puisieux; G Barratt
Journal: Antimicrob Agents Chemother Date: 2001-02 Impact factor: 5.191

4. Effect of amphotericin B on capsule and cell size in Cryptococcus neoformans during murine infection.

Authors: Oscar Zaragoza; Coralia Mihu; Arturo Casadevall; Joshua D Nosanchuk
Journal: Antimicrob Agents Chemother Date: 2005-10 Impact factor: 5.191

5. In vitro reversion of amphotericin B resistance in Leishmania donovani by poloxamer 188.

Authors: S Espuelas; P Legrand; P M Loiseau; C Bories; G Barratt; J M Irache
Journal: Antimicrob Agents Chemother Date: 2000-08 Impact factor: 5.191

6. Reactive oxygen intermediates, nitrite and IFN-gamma in Indian visceral leishmaniasis.

Authors: R Kumar; K Pai; S Sundar
Journal: Clin Exp Immunol Date: 2001-05 Impact factor: 4.330

Review 7. Amphotericin B membrane action: role for two types of ion channels in eliciting cell survival and lethal effects.

Authors: B Eleazar Cohen
Journal: J Membr Biol Date: 2010-11-18 Impact factor: 1.843