Literature DB >> 9257419

Facilitated analysis of data on drug regimen compliance.

E de Klerk1, S van der Linden, D van der Heijde, J Urquhart.   

Abstract

Drug actions depend on dose and intervals between doses, in ways that are drug-specific and sometimes complex, complicating the use of drug dosing histories as an explanatory variable in the analysis of clinical trials. We describe a spread-sheet method for conveniently displaying patients' drug dosing histories, to facilitate identification of dosing correlates of clinically important events.

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Year:  1997        PMID: 9257419     DOI: 10.1002/(sici)1097-0258(19970730)16:14<1653::aid-sim591>3.0.co;2-#

Source DB:  PubMed          Journal:  Stat Med        ISSN: 0277-6715            Impact factor:   2.373


  5 in total

Review 1.  The electronic medication event monitor. Lessons for pharmacotherapy.

Authors:  J Urquhart
Journal:  Clin Pharmacokinet       Date:  1997-05       Impact factor: 6.447

2.  Assessment of Markov-dependent stochastic models for drug administration compliance.

Authors:  Diane Wong; Reshma Modi; Murali Ramanathan
Journal:  Clin Pharmacokinet       Date:  2003       Impact factor: 6.447

3.  Estimation of population pharmacokinetic parameters in the presence of non-compliance.

Authors:  Song Mu; Thomas M Ludden
Journal:  J Pharmacokinet Pharmacodyn       Date:  2003-02       Impact factor: 2.745

4.  An internal pilot study for a randomized trial aimed at evaluating the effectiveness of iron interventions in children with non-anemic iron deficiency: the OptEC trial.

Authors:  Kawsari Abdullah; Kevin E Thorpe; Eva Mamak; Jonathon L Maguire; Catherine S Birken; Darcy Fehlings; Anthony J Hanley; Colin Macarthur; Stanley H Zlotkin; Patricia C Parkin
Journal:  Trials       Date:  2015-07-14       Impact factor: 2.279

5.  Optimizing early child development for young children with non-anemic iron deficiency in the primary care practice setting (OptEC): study protocol for a randomized controlled trial.

Authors:  Kawsari Abdullah; Kevin E Thorpe; Eva Mamak; Jonathon L Maguire; Catherine S Birken; Darcy Fehlings; Anthony J Hanley; Colin Macarthur; Stanley H Zlotkin; Patricia C Parkin
Journal:  Trials       Date:  2015-04-02       Impact factor: 2.279

  5 in total

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