M S Sokol1, N S Gray. 1. Eating Disorders Program, Menninger Clinic, Topeka, KS, USA. sokolms@menninger.edu
Abstract
OBJECTIVE: Certain cases of anorexia nervosa (AN) may be similar to the recently described subtype of childhood-onset obsessive-compulsive disorder hypothesized to be one of the pediatric infection-triggered autoimmune neuropsychiatric disorders (PITANDs). METHOD: Three clinical cases are reported. The first patient is a 12-year-old boy whose AN worsened acutely after a group A beta-hemolytic streptococcal (GABHS) infection. His symptoms were alleviated after antibiotic treatment. Two other patients with possible PITANDs-related AN are described. RESULTS: An infection-triggered process may contribute to the pathogenesis of a subtype of AN. CONCLUSIONS: Future research is needed to explore the nature of PITANDs and their relationship with AN.
OBJECTIVE: Certain cases of anorexia nervosa (AN) may be similar to the recently described subtype of childhood-onset obsessive-compulsive disorder hypothesized to be one of the pediatric infection-triggered autoimmune neuropsychiatric disorders (PITANDs). METHOD: Three clinical cases are reported. The first patient is a 12-year-old boy whose AN worsened acutely after a group A beta-hemolytic streptococcal (GABHS) infection. His symptoms were alleviated after antibiotic treatment. Two other patients with possible PITANDs-related AN are described. RESULTS: An infection-triggered process may contribute to the pathogenesis of a subtype of AN. CONCLUSIONS: Future research is needed to explore the nature of PITANDs and their relationship with AN.
Authors: Megan D Toufexis; Rebecca Hommer; Diana M Gerardi; Paul Grant; Leah Rothschild; Precilla D'Souza; Kyle Williams; James Leckman; Susan E Swedo; Tanya K Murphy Journal: J Child Adolesc Psychopharmacol Date: 2014-10-20 Impact factor: 2.576
Authors: Sergueï O Fetissov; Maria Hamze Sinno; Moïse Coëffier; Christine Bole-Feysot; Philippe Ducrotté; Tomas Hökfelt; Pierre Déchelotte Journal: Nutrition Date: 2008-02-08 Impact factor: 4.008