Literature DB >> 9256416

Three functional luciferase domains in a single polypeptide chain.

L Li1, R Hong, J W Hastings.   

Abstract

We report a unique case of a gene containing three homologous and contiguous repeat sequences, each of which, after excision, cloning, and expression in Escherichia coli, is shown to code for a peptide catalyzing the same reaction as the native protein, Gonyaulax polyedra luciferase (Mr = 137). This enzyme, which catalyzes the light-emitting oxidation of a linear tetrapyrrole (dinoflagellate luciferin), exhibits no sequence similarities to other luciferases in databases. Sequence analysis also reveals an unusual evolutionary feature of this gene: synonymous substitutions are strongly constrained in the central regions of each of the repeated coding sequences.

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Year:  1997        PMID： 9256416      PMCID： PMC22980          DOI： 10.1073/pnas.94.17.8954

Source DB:  PubMed          Journal:  Proc Natl Acad Sci U S A        ISSN： 0027-8424            Impact factor:   11.205


  19 in total

1.  Circadian regulation of bioluminescence in Gonyaulax involves translational control.

Authors:  D Morse; P M Milos; E Roux; J W Hastings
Journal:  Proc Natl Acad Sci U S A       Date:  1989-01       Impact factor: 11.205

2.  An active proteolytic fragment of Gonyaulax luciferase.

Authors:  N Krieger; D Njus; J W Hastings
Journal:  Biochemistry       Date:  1974-07-02       Impact factor: 3.162

3.  Bioluminescence: mechanism and mode of control of scintillon activity.

Authors:  M Fogel; J W Hastings
Journal:  Proc Natl Acad Sci U S A       Date:  1972-03       Impact factor: 11.205

4.  A stable, inexpensive, solid-state photomultiplier photometer.

Authors:  G W Mitchell; J W Hastings
Journal:  Anal Biochem       Date:  1971-01       Impact factor: 3.365

5.  Why genes in pieces?

Authors:  W Gilbert
Journal:  Nature       Date:  1978-02-09       Impact factor: 49.962

6.  Compartmentalization of algal bioluminescence: autofluorescence of bioluminescent particles in the dinoflagellate Gonyaulax as studied with image-intensified video microscopy and flow cytometry.

Authors:  C H Johnson; S Inoué; A Flint; J W Hastings
Journal:  J Cell Biol       Date:  1985-05       Impact factor: 10.539

Review 7.  Chemistries and colors of bioluminescent reactions: a review.

Authors:  J W Hastings
Journal:  Gene       Date:  1996       Impact factor: 3.688

8.  The biological clock in Gonyaulax controls luciferase activity by regulating turnover.

Authors:  J C Dunlap; J W Hastings
Journal:  J Biol Chem       Date:  1981-10-25       Impact factor: 5.157

9.  On the physical identity of scintillons: bioluminescent particles in Gonyaulax polyedra.

Authors:  M Fogel; R E Schmitter; J W Hastings
Journal:  J Cell Sci       Date:  1972-07       Impact factor: 5.285

10.  Characterization of the bioluminescent organelles in Gonyaulax polyedra (dinoflagellates) after fast-freeze fixation and antiluciferase immunogold staining.

Authors:  M T Nicolas; G Nicolas; C H Johnson; J M Bassot; J W Hastings
Journal:  J Cell Biol       Date:  1987-08       Impact factor: 10.539
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  10 in total

1.  Profile of J. Woodland Hastings.

Authors:  Tinsley H Davis
Journal:  Proc Natl Acad Sci U S A       Date:  2007-01-10       Impact factor: 11.205

2.  The structure and organization of the luciferase gene in the photosynthetic dinoflagellate Gonyaulax polyedra.

Authors:  L Li; J W Hastings
Journal:  Plant Mol Biol       Date:  1998-01       Impact factor: 4.076

3.  Crystal structure of a pH-regulated luciferase catalyzing the bioluminescent oxidation of an open tetrapyrrole.

Authors:  L Wayne Schultz; Liyun Liu; Margaret Cegielski; J Woodland Hastings
Journal:  Proc Natl Acad Sci U S A       Date:  2005-01-21       Impact factor: 11.205

4.  Two different domains of the luciferase gene in the heterotrophic dinoflagellate Noctiluca scintillans occur as two separate genes in photosynthetic species.

Authors:  Liyun Liu; J Woodland Hastings
Journal:  Proc Natl Acad Sci U S A       Date:  2006-11-27       Impact factor: 11.205

5.  Preparation and analysis of an expressed sequence tag library from the toxic dinoflagellate Alexandrium catenella.

Authors:  Paulina Uribe; Daniela Fuentes; Jorge Valdés; Amir Shmaryahu; Alicia Zúñiga; David Holmes; Pablo D T Valenzuela
Journal:  Mar Biotechnol (NY)       Date:  2008-05-14       Impact factor: 3.619

6.  Molecular evolution of dinoflagellate luciferases, enzymes with three catalytic domains in a single polypeptide.

Authors:  Liyun Liu; Thérèse Wilson; J Woodland Hastings
Journal:  Proc Natl Acad Sci U S A       Date:  2004-11-15       Impact factor: 11.205

7.  Identification and characterization of human polyserase-3, a novel protein with tandem serine-protease domains in the same polypeptide chain.

Authors:  Santiago Cal; Juan R Peinado; María Llamazares; Víctor Quesada; Angela Moncada-Pazos; Cecilia Garabaya; Carlos López-Otín
Journal:  BMC Biochem       Date:  2006-03-27       Impact factor: 4.059

8.  The alveolate translation initiation factor 4E family reveals a custom toolkit for translational control in core dinoflagellates.

Authors:  Grant D Jones; Ernest P Williams; Allen R Place; Rosemary Jagus; Tsvetan R Bachvaroff
Journal:  BMC Evol Biol       Date:  2015-02-10       Impact factor: 3.260

9.  Comparative transcriptome analysis of a toxin-producing dinoflagellate Alexandrium catenella and its non-toxic mutant.

Authors:  Yong Zhang; Shu-Fei Zhang; Lin Lin; Da-Zhi Wang
Journal:  Mar Drugs       Date:  2014-11-24       Impact factor: 5.118

Review 10.  Understanding Bioluminescence in Dinoflagellates-How Far Have We Come?

Authors:  Martha Valiadi; Debora Iglesias-Rodriguez
Journal:  Microorganisms       Date:  2013-09-05
  10 in total

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