Literature DB >> 9255862

1H-magnetic resonance spectroscopy in obsessive-compulsive disorder: evidence for neuronal loss in the cingulate gyrus and the right striatum.

D Ebert1, O Speck, A König, M Berger, J Hennig, F Hohagen.   

Abstract

We compared 12 patients with obsessive-compulsive disorder (OCD) and six control subjects by 1H-magnetic resonance spectroscopy. Significantly lower relative N-acetyl-aspartate (NAA) levels were found in the right striatum of OCD patients, as well as a decrease of anterior cingulate NAA that correlated with severity of illness. Age and sex were correlated to striatal NAA levels.

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Year:  1997        PMID： 9255862     DOI： 10.1016/s0925-4927(97)00016-4

Source DB:  PubMed          Journal:  Psychiatry Res        ISSN： 0165-1781            Impact factor:   3.222


  28 in total

1.  An Examination of Rostral Anterior Cingulate Cortex Function and Neurochemistry in Obsessive-Compulsive Disorder.

Authors:  Brian P Brennan; Olga Tkachenko; Zachary J Schwab; Richard J Juelich; Erin M Ryan; Alison J Athey; Harrison G Pope; Michael A Jenike; Justin T Baker; William D S Killgore; James I Hudson; J Eric Jensen; Scott L Rauch
Journal:  Neuropsychopharmacology       Date:  2015-02-09       Impact factor: 7.853

2.  1H-magnetic resonance spectroscopy in obsessive-compulsive disorder: effects of 12 weeks of sertraline treatment on brain metabolites.

Authors:  Raşit Tükel; Kubilay Aydın; Erhan Ertekin; Seda Şahin Özyıldırım; Mehmet Barburoğlu
Journal:  Eur Arch Psychiatry Clin Neurosci       Date:  2014-09-26       Impact factor: 5.270

3.  MRSI correlates of cognitive-behavioral therapy in pediatric obsessive-compulsive disorder.

Authors:  Joseph O'Neill; John C Piacentini; Susanna Chang; Jennifer G Levitt; Michelle Rozenman; Lindsey Bergman; Noriko Salamon; Jeffry R Alger; James T McCracken
Journal:  Prog Neuropsychopharmacol Biol Psychiatry       Date:  2011-10-01       Impact factor: 5.067

4.  Neurochemicals measured by (1)H-MR spectroscopy: putative vulnerability biomarkers for obsessive compulsive disorder.

Authors:  Sundar Gnanavel; Pratap Sharan; Sudhir Khandelwal; Uma Sharma; Naranamangalam R Jagannathan
Journal:  MAGMA       Date:  2013-12-12       Impact factor: 2.310

5.  Effects of intensive cognitive-behavioral therapy on cingulate neurochemistry in obsessive-compulsive disorder.

Authors:  Joseph O'Neill; Eda Gorbis; Jamie D Feusner; Jenny C Yip; Susanna Chang; Karron M Maidment; Jennifer G Levitt; Noriko Salamon; John M Ringman; Sanjaya Saxena
Journal:  J Psychiatr Res       Date:  2013-01-04       Impact factor: 4.791

Review 6.  Conjoint activity of anterior insular and anterior cingulate cortex: awareness and response.

Authors:  Nick Medford; Hugo D Critchley
Journal:  Brain Struct Funct       Date:  2010-05-29       Impact factor: 3.270

7.  Psychiatric comorbidity and functioning in a clinically referred population of adults with autism spectrum disorders: a comparative study.

Authors:  Gagan Joshi; Janet Wozniak; Carter Petty; Mary Kate Martelon; Ronna Fried; Anela Bolfek; Amelia Kotte; Jonathan Stevens; Stephannie L Furtak; Michelle Bourgeois; Janet Caruso; Ashley Caron; Joseph Biederman
Journal:  J Autism Dev Disord       Date:  2013-06

Review 8.  The neurocircuitry of fear, stress, and anxiety disorders.

Authors:  Lisa M Shin; Israel Liberzon
Journal:  Neuropsychopharmacology       Date:  2010-01       Impact factor: 7.853

Review 9.  Glutamate-modulating drugs as novel pharmacotherapeutic agents in the treatment of obsessive-compulsive disorder.

Authors:  Christopher Pittenger; John H Krystal; Vladimir Coric
Journal:  NeuroRx       Date:  2006-01

10.  Glutamatergic Synaptic Dysfunction and Obsessive-Compulsive Disorder.

Authors:  Jonathan T Ting; Guoping Feng
Journal:  Curr Chem Genomics       Date:  2008-01-01
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