| Literature DB >> 9253406 |
L Huang, X Weng, F Hofer, G S Martin, S H Kim.
Abstract
The Ras-interacting domains of the the protein-kinase Raf and the Ral guanine nucleotide dissociation stimulator, RalGDS, lack extensive sequence similarity, but their overall three-dimensional structures are very similar to each other. Mutational analysis indicated that three residues in the RalGDS domain are critical for its interaction with Ras.Entities:
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Year: 1997 PMID: 9253406 DOI: 10.1038/nsb0897-609
Source DB: PubMed Journal: Nat Struct Biol ISSN: 1072-8368