Literature DB >> 92509

Intrathymic injection of antigen: a potent procedure for the induction of suppressor T cells.

M Shimizu, T Kimura, M Kakinuma, T Ohara.   

Abstract

Immunological tolerance is induced in mice by intrathymic injection of HSA. The tolerance thus induced is mediated by suppressor T cells. Strong tolerance persists more than 56 days after the induction, and the high efficiency of the tolerance thus induced is accounted for in terms of the number or the potentiality of suppressor cells. Possible mechanisms of suppressor T cell induction by iT injection of the antigen are discussed briefly.

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Year:  1979        PMID: 92509     DOI: 10.1016/0022-1759(79)90284-9

Source DB:  PubMed          Journal:  J Immunol Methods        ISSN: 0022-1759            Impact factor:   2.303


  3 in total

1.  Anti-acetylcholine receptor antibodies induced in mice by syngeneic receptor without adjuvants.

Authors:  G K Scadding; L Calder; A Vincent; C Prior; D Wray; J Newsom-Davis
Journal:  Immunology       Date:  1986-05       Impact factor: 7.397

2.  'Split tolerance' induction by intrathymic injection of acetylcholine receptor in a rat model of autoimmune myasthenia gravis; implications for the design of specific immunotherapies.

Authors:  I Ohtsuru; H Matsuo; T Fukudome; A Suenaga; M Tsujihata; S Nagataki
Journal:  Clin Exp Immunol       Date:  1995-12       Impact factor: 4.330

Review 3.  Mechanisms of Tolerance Induction by Hematopoietic Chimerism: The Immune Perspective.

Authors:  Esma S Yolcu; Haval Shirwan; Nadir Askenasy
Journal:  Stem Cells Transl Med       Date:  2017-01-03       Impact factor: 6.940

  3 in total

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