| Literature DB >> 9249978 |
W G Kim1, I K Lee, J P Kim, I J Ryoo, H Koshino, I D Yoo.
Abstract
Two new indole derivatives were isolated as free radical scavengers from the MeOH extract of Agrocybe cylindracea. The structures of these compounds were determined to be 6-hydroxy-1H-indole-3-carboxaldehyde (1) and 6-hydroxy-1H-indole-3-acetamide (2) on the basis of spectroscopic studies. Compounds 1 and 2 inhibited lipid peroxidation in rat liver microsomes, with IC50 values of 4.1 and 3.9 micrograms/mL, respectively.Entities:
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Year: 1997 PMID: 9249978 DOI: 10.1021/np970150w
Source DB: PubMed Journal: J Nat Prod ISSN: 0163-3864 Impact factor: 4.050