Literature DB >> 9249975

Inhibitory effect of dehydroevodiamine and evodiamine on nitric oxide production in cultured murine macrophages.

W F Chiou1, Y J Sung, J F Liao, A Y Shum, C F Chen.   

Abstract

Possible antiinflammatory effects of dehydroevodiamine (1) and evodiamine (2) were examined by assessing their effects on NO production in the murine macrophage-like cell line RAW 264.7. The results indicated that both 1 and 2 inhibited the IFN-gamma/LPS-stimulated NO production in a concentration-dependent manner. However, 1 appeared to inhibit NO production by interfering not only with the priming signal initiated by IFN-gamma but also with iNOS protein synthesis, while 2 affected the former only.

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Year:  1997        PMID： 9249975     DOI： 10.1021/np960495z

Source DB:  PubMed          Journal:  J Nat Prod        ISSN： 0163-3864            Impact factor:   4.050


  19 in total

1.  Cryptochrome in sponges: a key molecule linking photoreception with phototransduction.

Authors:  Werner E G Müller; Heinz C Schröder; Julia S Markl; Vlad A Grebenjuk; Michael Korzhev; Renate Steffen; Xiaohong Wang
Journal:  J Histochem Cytochem       Date:  2013-08-06       Impact factor: 2.479

2.  Evodiamine Inhibits Zymosan-Induced Inflammation In Vitro and In Vivo: Inactivation of NF-κB by Inhibiting IκBα Phosphorylation.

Authors:  Xia Fan; Jun-Yu Zhu; Yu Sun; Li Luo; Jun Yan; Xue Yang; Jing Yu; Wan-Qi Tang; Wei Ma; Hua-Ping Liang
Journal:  Inflammation       Date:  2017-06       Impact factor: 4.092

3.  Mechanisms of suppression of inducible nitric oxide synthase (iNOS) expression in RAW 264.7 cells by andrographolide.

Authors:  W F Chiou; C F Chen; J J Lin
Journal:  Br J Pharmacol       Date:  2000-04       Impact factor: 8.739

4.  Evodiamine ameliorates liver fibrosis in rats via TGF-β1/Smad signaling pathway.

Authors:  Dongmei Yang; Li Li; Shanjun Qian; Lixin Liu
Journal:  J Nat Med       Date:  2017-09-21       Impact factor: 2.343

5.  Apoptosis of human non-small-cell lung cancer A549 cells triggered by evodiamine through MTDH-dependent signaling pathway.

Authors:  Yanmei Zou; Xiaomin Qin; Hua Xiong; Feng Zhu; Tao Chen; Hongge Wu
Journal:  Tumour Biol       Date:  2015-02-05

6.  Nepalolide A inhibits the expression of inducible nitric oxide synthase by modulating the degradation of IkappaB-alpha and IkappaB-beta in C6 glioma cells and rat primary astrocytes.

Authors:  C N Wang; Y J Shiao; Y L Lin; C F Chen
Journal:  Br J Pharmacol       Date:  1999-09       Impact factor: 8.739

7.  Effects of dehydroevodiamine exposure on glutamate release and uptake in the cultured cerebellar cells.

Authors:  Dong Koo Lim; Yong Bok Lee; Han Soo Kim
Journal:  Neurochem Res       Date:  2004-02       Impact factor: 3.996

8.  Preparation of evodiamine solid dispersions and its pharmacokinetics.

Authors:  H Xu; T Zhang; H Yang; X Xiao; Y Bian; D Si; C Liu
Journal:  Indian J Pharm Sci       Date:  2011-05       Impact factor: 0.975

9.  Evodia rutaecarpa and Three Major Alkaloids Abrogate Influenza A Virus (H1N1)-Induced Chemokines Production and Cell Migration.

Authors:  Wen-Fei Chiou; Han-Chieh Ko; Bai-Luh Wei
Journal:  Evid Based Complement Alternat Med       Date:  2011-06-08       Impact factor: 2.629

10.  Activation of TRPV1 prevents OxLDL-induced lipid accumulation and TNF-α-induced inflammation in macrophages: role of liver X receptor α.

Authors:  Jin-Feng Zhao; Li-Chieh Ching; Yu Ru Kou; Shing-Jong Lin; Jeng Wei; Song-Kun Shyue; Tzong-Shyuan Lee
Journal:  Mediators Inflamm       Date:  2013-06-26       Impact factor: 4.711
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