Literature DB >> 9249756

Dipolar cycloadditions in solid-phase organic synthesis (SPOS).

E J Kantorowski1, M J Kurth.   

Abstract

We present a concise review of polymer-supported 1,3-dipolar cycloaddition reactions. Nitrile oxide and azomethine ylides constitute the two types of 1,3-dipoles which have been used in conjunction with solid-phase organic synthesis. These cycloaddition reactions on solid phase are generally of equal or greater efficiency than the analogous solution-phase reactions.

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Year:  1997        PMID： 9249756     DOI： 10.1007/bf01715636

Source DB:  PubMed          Journal:  Mol Divers        ISSN： 1381-1991            Impact factor:   2.943


  11 in total

1.  Synthesis and Applications of Small Molecule Libraries.

Authors:  Lorin A. Thompson; Jonathan A. Ellman
Journal:  Chem Rev       Date:  1996-02-01       Impact factor: 60.622

2.  Reissert-Based "Traceless" Solid-Phase Synthesis: Isoquinoline, and Isoxazoline-Containing Heterocycles.

Authors:  Beth A. Lorsbach; R. Bryan Miller; Mark J. Kurth
Journal:  J Org Chem       Date:  1996-12-13       Impact factor: 4.354

3.  Solid-Phase Combinatorial Synthesis of Polyisoxazolines: A Two-Reaction Iterative Protocol.

Authors:  Mark J. Kurth; Lisa A. Ahlberg Randall; Kazuya Takenouchi
Journal:  J Org Chem       Date:  1996-12-13       Impact factor: 4.354

4.  General method for rapid synthesis of multicomponent peptide mixtures.

Authors:  A Furka; F Sebestyén; M Asgedom; G Dibó
Journal:  Int J Pept Protein Res       Date:  1991-06

5.  Conformationally restricted analogues of disoxaril: a comparison of the activity against human rhinovirus types 14 and 1A.

Authors:  J P Mallamo; G D Diana; D C Pevear; F J Dutko; M S Chapman; K H Kim; I Minor; M Oliveira; M G Rossmann
Journal:  J Med Chem       Date:  1992-12-11       Impact factor: 7.446

6.  Excitatory amino acid receptor ligands. Synthesis and biological activity of 3-isoxazolol amino acids structurally related to homoibotenic acid.

Authors:  I T Christensen; B Ebert; U Madsen; B Nielsen; L Brehm; P Krogsgaard-Larsen
Journal:  J Med Chem       Date:  1992-09-18       Impact factor: 7.446

Review 7.  Angiotensin-converting enzyme inhibitors: medicinal chemistry and biological actions.

Authors:  E W Petrillo; M A Ondetti
Journal:  Med Res Rev       Date:  1982 Jan-Mar       Impact factor: 12.944

8.  Studies on uricosuric diuretics. 4. Three-dimensional structure-activity relationships and receptor mapping of (aryloxy)acetic acid diuretics.

Authors:  H Koga; H Sato; T Dan; B Aoki
Journal:  J Med Chem       Date:  1991-09       Impact factor: 7.446

9.  N-(4-Isoxazolylthiazol-2-yl)oxamic acid derivatives as potent orally active antianaphylactic agents.

Authors:  D Chiarino; G Grancini; V Frigeni; I Biasini; A Carenzi
Journal:  J Med Chem       Date:  1991-02       Impact factor: 7.446

10.  Pyrrolidine dithiocarbamate inhibits intercellular adhesion molecule-1 biosynthesis induced by cytokines in human fibroblasts.

Authors:  M Kawai; R Nishikomori; E Y Jung; G Tai; C Yamanaka; M Mayumi; T Heike
Journal:  J Immunol       Date:  1995-03-01       Impact factor: 5.422
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  3 in total

1.  Fluorous mixture synthesis of two libraries with hydantoin-, and benzodiazepinedione-fused heterocyclic scaffolds.

Authors:  Wei Zhang; Yimin Lu; Christine Hiu-Tung Chen; Lu Zeng; Daniel B Kassel
Journal:  J Comb Chem       Date:  2006 Sep-Oct

Review 2.  Recent advances in 1,3-dipolar cycloaddition reactions on solid supports.

Authors:  Kirsi Harju; Jari Yli-Kauhaluoma
Journal:  Mol Divers       Date:  2005       Impact factor: 2.943

3.  Fluorous Synthesis of Hydantoin-, Piperazinedione-, and Benzodiazepinedione-Fused Tricyclic and Tetracyclic Ring Systems.

Authors:  Wei Zhang; Yimin Lu; Christine Hiu-Tung Chen; Dennis P Curran; Steven Geib
Journal:  European J Org Chem       Date:  2006
  3 in total

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