BACKGROUND: Among the different modalities for treatment of cutaneous leishmaniasis, liquid nitrogen is considered an effective therapy with very mild side-effects. METHODS: A study was conducted using liquid nitrogen topically for the treatment of cutaneous leishmaniasis in the King Hussain Medical Centre, Amman-Jordan. Among 468 patients of cutaneous leishmaniasis, 293 were treated with liquid nitrogen and the rest were treated with other known treatment modalities. RESULTS: Of the patients treated with cryo surgery liquid nitrogen, 215 of 293 permitted appropriate follow-up; the clinical response was significant and effective. No systemic adverse effects were noted. Mild cutaneous complications were infrequent, and included hypopigmentation, hyperpigmentation, and scar formation. CONCLUSIONS: From the results of this study, liquid nitrogen therapy may be considered an effective treatment for cutaneous leishmaniasis.
BACKGROUND: Among the different modalities for treatment of cutaneous leishmaniasis, liquid nitrogen is considered an effective therapy with very mild side-effects. METHODS: A study was conducted using liquid nitrogen topically for the treatment of cutaneous leishmaniasis in the King Hussain Medical Centre, Amman-Jordan. Among 468 patients of cutaneous leishmaniasis, 293 were treated with liquid nitrogen and the rest were treated with other known treatment modalities. RESULTS: Of the patients treated with cryo surgery liquid nitrogen, 215 of 293 permitted appropriate follow-up; the clinical response was significant and effective. No systemic adverse effects were noted. Mild cutaneous complications were infrequent, and included hypopigmentation, hyperpigmentation, and scar formation. CONCLUSIONS: From the results of this study, liquid nitrogen therapy may be considered an effective treatment for cutaneous leishmaniasis.
Authors: Saeedeh Farajzadeh; Maryam Hakimi Parizi; Ali Akbar Haghdoost; Azadeh Mohebbi; Saman Mohammadi; Abbas Pardakhty; Sana Eybpoosh; Amireh Heshmatkhah; Behrooz Vares; Simin Saryazdi; Ali Reza Fekri; Elham Mohebbi Journal: J Parasit Dis Date: 2014-11-22