Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 Uptake of peroxidase by calcitonin inhibited osteoclasts.

Literature DB >> 924813

Uptake of peroxidase by calcitonin inhibited osteoclasts.

Abstract

The present electron microscopic histochemical study demonstrates that osteoclasts from calcitonin treated bone are able to take up organic macromolecules even though the ruffled border has disapppeared. The absorption occurs around the entire periphery of the osteoclast, but the amount of absorbed peroxidase seems to be reduced in comparison with that of untreated cells. It is concluded that the effect of calcitonin on osteoclasts is primarily a cessation of the exocytosis and the concomitant disappearance of the ruffled border.

Mesh：

Substances：
Calcitonin
Peroxidases

Year: 1977 PMID： 924813 DOI： 10.1007/bf00489672

Source DB: PubMed Journal: Histochemistry ISSN： 0301-5564

15 in total

1. Export of protein from the osteoclast as studied by electron microscopic autoradiography.

Authors: U Lucht; J O Norgaard
Journal: Cell Tissue Res Date: 1976-04-28 Impact factor: 5.249

Review 2. Calcitonin.

Authors: C S Anast; H H Conaway
Journal: Clin Orthop Relat Res Date: 1972-05 Impact factor: 4.176

8. The early stages of absorption of injected horseradish peroxidase in the proximal tubules of mouse kidney: ultrastructural cytochemistry by a new technique.

Authors: R C Graham; M J Karnovsky
Journal: J Histochem Cytochem Date: 1966-04 Impact factor: 2.479

Uptake of peroxidase by calcitonin inhibited osteoclasts.

1. Export of protein from the osteoclast as studied by electron microscopic autoradiography.

Review 2. Calcitonin.

3. Effects of parathyroid hormone on osteoclasts in vivo. An ultrastructural and histochemical study.

4. Electron microscopic localization of hydrolytic enzymes in osteoclasts.

5. Evidence of coated membranes in the ruffled border of the osteoclast.

6. Inhibitory actions of calcitonin on resorbing bone explants in culture and on their release of lysosomal hydrolases.

7. Absorption of peroxidase by osteoclasts as studied by electron microscope histochemistry.

8. The early stages of absorption of injected horseradish peroxidase in the proximal tubules of mouse kidney: ultrastructural cytochemistry by a new technique.

9. The osteoclast: review of ultrastructure, origin, and structure-function relationship.

10. Functions of coated vesicles during protein absorption in the rat vas deferens.

1. Uptake of horseradish peroxidase by bone cells during endochondral bone development.

2. Motility and resorption: osteoclastic activity in vitro.