| Literature DB >> 9247892 |
Abstract
Although there are recognized risk factors for breast cancer, its cause is still unknown. It is hypothesized here that breast cancer results from late exposure to a common virus. This hypothesis is investigated by relating the epidemiology of breast cancer to the seroepidemiology of cytomegalovirus, as a surrogate for a breast cancer virus. The hypothesis is consistent with the geographical distribution of breast cancer; a correlation between breast cancer incidence and the percentage of adults who are cytomegalovirus seropositive in various countries was found (Pearson correlation coefficient -0.79). The hypothesis is also consistent with other risk factors for breast cancer, such as age at onset, family history, hormonal factors and migration.Entities:
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Year: 1997 PMID: 9247892 DOI: 10.1016/s0306-9877(97)90118-3
Source DB: PubMed Journal: Med Hypotheses ISSN: 0306-9877 Impact factor: 1.538