Literature DB >> 9246281

The effectiveness of topical diclofenac in relieving discomfort following traumatic corneal abrasions.

D G Jayamanne1, A W Fitt, M Dayan, R M Andrews, K W Mitchell, P G Griffiths.   

Abstract

Diclofenac is a non-steroidal anti-inflammatory drug available in an ophthalmic preparation. We present a prospective randomised double-masked placebo-controlled trial involving 40 patients that assessed the effectiveness of topical diclofenac in relieving pain from traumatic corneal abrasions. Statistical analysis of visual analogue and categorical pain scores revealed a significant reduction in pain experienced by subjects in the diclofenac group (p < 0.02).

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Year:  1997        PMID: 9246281     DOI: 10.1038/eye.1997.15

Source DB:  PubMed          Journal:  Eye (Lond)        ISSN: 0950-222X            Impact factor:   3.775


  4 in total

1.  Towards evidence based emergency medicine: best BETs from the Manchester Royal Infirmary. Topical analgesia in corneal abrasions.

Authors:  S Carley
Journal:  J Accid Emerg Med       Date:  1999-01

2.  Corneal abrasion.

Authors:  Scott Fraser
Journal:  Clin Ophthalmol       Date:  2010-05-06

Review 3.  Efficacy of Topical Analgesics in Pain Control for Corneal Abrasions: A Systematic Review.

Authors:  Bryan Thiel; Alexandra Sarau; Daniel Ng
Journal:  Cureus       Date:  2017-03-27

Review 4.  The Role of the P2X7 Receptor in Ocular Stresses: A Potential Therapeutic Target.

Authors:  Mélody Dutot; Elodie Olivier; Anaïs Wakx; Patrice Rat
Journal:  Vision (Basel)       Date:  2017-05-17
  4 in total

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