Literature DB >> 9245694

Peroxynitrite scavenging by flavonoids.

G R Haenen1, J B Paquay, R E Korthouwer, A Bast.   

Abstract

The peroxynitrite scavenging activity of a series of structurally related flavonoids was tested. It was found that flavonoids are excellent scavengers of peroxynitrite. Compared to the known peroxynitrite scavenger ebselen, the most active flavonoids proved to be 10 times more effective. Indications were found that the catechol group (ring B) and the hydroxyl group at position 3 give the highest contribution to the peroxynitrite scavenging effect. The peroxynitrite scavenging is discussed in relation to the beneficial effect of flavonoid intake on the incidence of coronary heart disease.

Entities:  

Mesh：

Substances：

Year:  1997        PMID： 9245694     DOI： 10.1006/bbrc.1997.7016

Source DB:  PubMed          Journal:  Biochem Biophys Res Commun        ISSN： 0006-291X            Impact factor:   3.575


  28 in total

1.  Citrus flavonoids luteolin, apigenin, and quercetin inhibit glycogen synthase kinase-3β enzymatic activity by lowering the interaction energy within the binding cavity.

Authors:  Jodee L Johnson; Sanjeewa G Rupasinghe; Felicia Stefani; Mary A Schuler; Elvira Gonzalez de Mejia
Journal:  J Med Food       Date:  2011-04       Impact factor: 2.786

2.  Protective effect of catechin on pentachlorophenol-induced cytotoxicity and genotoxicity in isolated human blood cells.

Authors:  Nikhil Maheshwari; Riaz Mahmood
Journal:  Environ Sci Pollut Res Int       Date:  2020-02-08       Impact factor: 4.223

3.  Rutin stimulates sarcoplasmic reticulum Ca(2+)-ATPase activity (SERCA1) and protects SERCA1 from peroxynitrite mediated injury.

Authors:  Jana Viskupicova; Miriam K Strosova; Petronela Zizkova; Magdalena Majekova; Lubica Horakova
Journal:  Mol Cell Biochem       Date:  2014-12-30       Impact factor: 3.396

4.  Green tea polyphenols function as prooxidants to activate oxidative-stress-responsive transcription factors in yeasts.

Authors:  Kazuhiro Maeta; Wataru Nomura; Yoshifumi Takatsume; Shingo Izawa; Yoshiharu Inoue
Journal:  Appl Environ Microbiol       Date:  2006-11-22       Impact factor: 4.792

5.  Naringin Protects against Rotenone-induced Apoptosis in Human Neuroblastoma SH-SY5Y Cells.

Authors:  Hak-Jae Kim; Jeong Yoon Song; Hae Jeong Park; Hyun-Kyung Park; Dong Hwan Yun; Joo-Ho Chung
Journal:  Korean J Physiol Pharmacol       Date:  2009-08-31       Impact factor: 2.016

Review 6.  Flavonoids as anti-inflammatory agents: implications in cancer and cardiovascular disease.

Authors:  Ana García-Lafuente; Eva Guillamón; Ana Villares; Mauricio A Rostagno; José Alfredo Martínez
Journal:  Inflamm Res       Date:  2009-04-21       Impact factor: 4.575

Review 7.  Role of nitric oxide synthases in Parkinson's disease: a review on the antioxidant and anti-inflammatory activity of polyphenols.

Authors:  Katia Aquilano; Sara Baldelli; Giuseppe Rotilio; Maria Rosa Ciriolo
Journal:  Neurochem Res       Date:  2008-04-16       Impact factor: 3.996

8.  Intravenous rutin in rat exacerbates isoprenaline-induced cardiotoxicity likely due to intracellular oxidative stress.

Authors:  Tomáš Filipský; Michal Říha; Pavlína Hašková; Veronika Pilařová; Lucie Nováková; Vladimír Semecký; Jaroslava Vávrová; Magdaléna Holečková; Vladimir Palicka; Tomáš Šimůnek; Radomír Hrdina; Přemysl Mladěnka
Journal:  Redox Rep       Date:  2016-03-21       Impact factor: 4.412

9.  Entacapone scavenges peroxynitrite and protects against kidney and liver injuries induced by renal ischemia/reperfusion in rats.

Authors:  Eman Soliman; Samar M Shewaikh; Ahmed Fahmy; Shimaa Elshazly
Journal:  Int Urol Nephrol       Date:  2021-03-06       Impact factor: 2.370

10.  Protective Effect of ECQ on Rat Reflux Esophagitis Model.

Authors:  Hyeon-Soon Jang; Jeong Hoon Han; Jun Yeong Jeong; Uy Dong Sohn
Journal:  Korean J Physiol Pharmacol       Date:  2012-12-10       Impact factor: 2.016
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.