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Literature DB >> 924446

Cell division and sister chromatid exchanges in 45,X/46,Xi(Xq) mosaicism.

Abstract

The kinetics of cell division and sister chromatid exchanges were studied in PHA-stimulated short-term cultivations of peripheral blood by means of the BUDR/FPG technique in controls and in five patients with 45,X/46,X,i(Xq) mosaicism. No significant difference in the length of the cell cycle were observed between 45,X/46,X,i(Xq) and control 46,XX cells. The number of SCE on late i(Xq) was only nonsignificantly elevated (0.6 per i(Xq) against the value expected on the basis of its relative length.

Entities: Mutation Species

Mesh：

Substances：
Lectins

Year: 1977 PMID： 924446 DOI： 10.1007/bf00273155

Source DB: PubMed Journal: Hum Genet ISSN： 0340-6717 Impact factor: 4.132

13 in total

3. Increased sister chromatid exchanges in human cell lines characterized by monosomy X or structural abnormalities of the X chromosome.

Authors: M A Iqbal; A O Martin; J L Simpson
Journal: Hum Genet Date: 1984 Impact factor: 4.132

3 in total

Cell division and sister chromatid exchanges in 45,X/46,Xi(Xq) mosaicism.

1. Heterochromatin and sister chromatid exchanges in the chromosomes of Microtus agrestis.

2. Trisomy 8 restricted to cultured fibroblasts.

3. A simple technique for demonstrating centromeric heterochromatin.

4. New technique for distinguishing between human chromosomes.

5. Analysis of human metaphase chromosome set by aid of DNA-binding fluorescent agents.

6. Disappearance of a 47,XX,C+ leucocyte cell line in an infant who had previously exhibited 46,XX-47,XX,C+ mosaicism.

7. A manyfold increase in sister chromatid exchanges in Bloom's syndrome lymphocytes.

8. Differences in human X isochromosomes.

9. Sister chromatid exchanges and chromatid interchanges in bloom's syndrome.

10. Increased sister chromatid exchange events in the human late replicating X.

1. The Turner phenotype and the different types of human x isochromosome.

2. Frequency of sister chromatid exchanges in a balanced reciprocal whole-arm translocation.

3. Increased sister chromatid exchanges in human cell lines characterized by monosomy X or structural abnormalities of the X chromosome.