Literature DB >> 9243401

Paradoxic uptake of Gd-EOB-DTPA by hepatocellular carcinoma in mice: quantitative image analysis.

M Fujita1, R Yamamoto, M Takahashi, T Tsuji, T Yamanaka, T Miyazawa, B Fritz-Zieroth, N Terada, C Kuroda.   

Abstract

To determine whether paradoxic uptake of gadolinium-ethoxybenzyl-diethylenetriamine pentaacetic acid (Gd-EOB-DTPA) occurs only with highly differentiated hepatocellular carcinomas, quantitative image analysis was performed in 37 mice with 133 hepatocellular carcinomas. The results of lesion/ liver signal intensity measurement and relative enhancement calculation indicate that paradoxic positive enhancement occurs independently of cellular differentiation.

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Year:  1997        PMID： 9243401     DOI： 10.1002/jmri.1880070426

Source DB:  PubMed          Journal:  J Magn Reson Imaging        ISSN： 1053-1807            Impact factor:   4.813


  6 in total

Review 1.  [Current status of MRI diagnostics with liver-specific contrast agents. Gd-EOB-DTPA and Gd-BOPTA].

Authors:  C Stroszczynski; G Gaffke; M Gnauck; F Streitparth; G Wieners; E Lopez-Häninnen
Journal:  Radiologe       Date:  2004-12       Impact factor: 0.635

Review 2.  Appearance of hepatocellular carcinoma on gadoxetic acid-enhanced hepato-biliary phase MR imaging: a systematic review.

Authors:  Paola Erra; Marta Puglia; Alfonso Ragozzino; Simone Maurea; Raffaele Liuzzi; Giuseppe Sabino; Luigi Barbuto; Alberto Cuocolo; Massimo Imbriaco
Journal:  Radiol Med       Date:  2015-04-22       Impact factor: 3.469

3.  Proper definitions of MRI contrast enhancement in liver tumors.

Authors:  Yicheng Ni; Feng Chen; Huaijun Wang; Yuanbo Feng; Junjie Li; Yansheng Jiang
Journal:  J Gastroenterol       Date:  2009-12-15       Impact factor: 7.527

4.  Detection and characterization of liver lesions using gadoxetic acid as a tissue-specific contrast agent.

Authors:  Peter Reimer; Rolf Vosshenrich
Journal:  Biologics       Date:  2010-08-09

5.  Expression of OATP1B3 determines uptake of Gd-EOB-DTPA in hepatocellular carcinoma.

Authors:  Masato Narita; Etsuro Hatano; Shigeki Arizono; Aya Miyagawa-Hayashino; Hiroyoshi Isoda; Koji Kitamura; Kojiro Taura; Kentaro Yasuchika; Takashi Nitta; Iwao Ikai; Shinji Uemoto
Journal:  J Gastroenterol       Date:  2009-04-29       Impact factor: 7.527

6.  Gadoxetate acid-enhanced MRI of hepatocellular carcinoma in a c-myc/TGFα transgenic mouse model including signal intensity and fat content: initial experience.

Authors:  Huedayi Korkusuz; Lea Knau; Wolfgang Kromen; Frank Huebner; Renate Hammerstingl; Sebastian Lindemayr; Verena Bihrer; Albrecht Piiper; Thomas J Vogl
Journal:  Cancer Imaging       Date:  2012-03-07       Impact factor: 3.909
  6 in total

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