Biochemical dehydrogenations of saccharides. IX. D-lyxo-5-hexulosonic acid from D-mannose by Acetomonas oxydans fermentation.

Fermentation of nutrient media by a selected strain of Acetomonas oxydans with a continuous pH control gave D-lyxo-5-hexulosonate in the form of a calcium or potassium salt with a yield equal to 95% of theory. The media contained up to 20 g D-mannose per 100 ml and a small amount of a readily assimilated monosaccharide.