Literature DB >> 9241615

In vivo development of antibody to interferons: an update to 1996.

G Antonelli1.   

Abstract

It has been well established that a percentage of patients receiving interferon (IFN) produce antibodies that can neutralize its action or bind to the molecule. There are also indications that the development of neutralizing antibodies to IFN may be associated with failure of IFN therapy. This article reviews such observations and addresses some of the continuing questions on this issue.

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Year:  1997        PMID: 9241615

Source DB:  PubMed          Journal:  J Interferon Cytokine Res        ISSN: 1079-9907            Impact factor:   2.607


  3 in total

1.  Serum interferon (IFN)-neutralizing antibodies and bioactivities of IFNs in patients with severe type II essential mixed cryoglobulinemia.

Authors:  Carolina Scagnolari; Milvia Casato; Francesca Bellomi; Francesca De Pisa; Ombretta Turriziani; Rossella Coviello; Maria Rosaria Pirro; Ferdinando Dianzani; Guido Antonelli
Journal:  Clin Diagn Lab Immunol       Date:  2003-01

2.  Hypothetical review: thymic aberrations and type-I interferons; attempts to deduce autoimmunizing mechanisms from unexpected clues in monogenic and paraneoplastic syndromes.

Authors:  A Meager; P Peterson; N Willcox
Journal:  Clin Exp Immunol       Date:  2008-08-22       Impact factor: 4.330

Review 3.  Safety, Tolerability, and Immunogenicity of Interferons.

Authors:  Michael G Tovey; Christophe Lallemand
Journal:  Pharmaceuticals (Basel)       Date:  2010-04-20
  3 in total

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