Literature DB >> 9240358

Novel non-nucleoside inhibitors of human immunodeficiency virus type 1 reverse transcriptase. 6. 2-Indol-3-yl- and 2-azaindol-3-yl-dipyridodiazepinones.

T A Kelly1, D W McNeil, J M Rose, E David, C K Shih, P M Grob.   

Abstract

Modification of the non-nucleoside inhibitor of HIV-1 reverse transcriptase nevirapine (Viramune) by incorporation of a 2-indolyl substituent confers activity against several mutant forms of the enzyme.

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Year:  1997        PMID： 9240358     DOI： 10.1021/jm960837y

Source DB:  PubMed          Journal:  J Med Chem        ISSN： 0022-2623            Impact factor:   7.446


  3 in total

1.  Racemic 9,10-dimeth-oxy-3-methyl-6-phenyl-7,7a-dihydro-benzo[b]benzo[4,5]isothia-zolo[2,3-d][1,4]diazepine 12,12-dioxide.

Authors:  Jatinder P Bassin; Virender P Shah; Lee Martin; Peter N Horton
Journal:  Acta Crystallogr Sect E Struct Rep Online       Date:  2011-02-23

2.  Total synthesis and antiviral activity of indolosesquiterpenoids from the xiamycin and oridamycin families.

Authors:  Zhanchao Meng; Haixin Yu; Li Li; Wanyin Tao; Hao Chen; Ming Wan; Peng Yang; David J Edmonds; Jin Zhong; Ang Li
Journal:  Nat Commun       Date:  2015-02-04       Impact factor: 14.919

3.  Dipyridodiazepinone derivatives; synthesis and anti HIV-1 activity.

Authors:  Nisachon Khunnawutmanotham; Nitirat Chimnoi; Arunee Thitithanyanont; Patchreenart Saparpakorn; Kiattawee Choowongkomon; Pornpan Pungpo; Supa Hannongbua; Supanna Techasakul
Journal:  Beilstein J Org Chem       Date:  2009-07-22       Impact factor: 2.883
  3 in total

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