Literature DB >> 923721

Effect of clonidine on the noradrenergic cyclic AMP generating system in the limbic forebrain and on medial forebrain bundle self-stimulation behavior.

J Vetulani, N J Leith, R J Stawarz, F Sulser.   

Abstract

The present results show that clonidine does not mimic the agonist action of norepinephrine (NE) on the noradrenergic cyclic AMP generating system of the limbic forebrain, but antagonizes the stimulatory effect of NE while not influencing the action of isoprenaline. In self-stimulation behavior, clonidine decreases responding and blocks the facilitation caused by d-amphetamine.

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Year:  1977        PMID： 923721     DOI： 10.1007/bf01918827

Source DB:  PubMed          Journal:  Experientia        ISSN： 0014-4754


  15 in total

1.  The noradrenergic cyclic AMP generating system in the limbic forebrain: pharmacological characterization in vitro and possible role of limbic noradrenergic mechanisms in the mode of action of antipsychotics.

Authors:  J B Blumberg; J Vetulani; R J Stawarz; F Sulser
Journal:  Eur J Pharmacol       Date:  1976-06       Impact factor: 4.432

Review 2.  Norepinephrine reward pathways: role of self-stimulation, memory consolidation, and schizophrenia.

Authors:  L Stein
Journal:  Nebr Symp Motiv       Date:  1975

3.  Amphetamine and the reward system: evidence for tolerance and post-drug depression.

Authors:  N J Leith; R J Barrett
Journal:  Psychopharmacologia       Date:  1976

4.  Adaptive mechanisms of the noradrenergic cyclic AMP generating system in the limbic forebrain of the rat: adaptation to persistent changes in the availability of norepinephrine (NE).

Authors:  J Vetulani; R J Stawarz; F Sulser
Journal:  J Neurochem       Date:  1976-09       Impact factor: 5.372

5.  Stimulation of adenosine 3',5'-monophosphate formation by alpha and beta adrenergic agonists in rat cerebral cortical slices: effects of clonidine.

Authors:  P Skolnick; J W Daly
Journal:  Mol Pharmacol       Date:  1975-09       Impact factor: 4.436

6.  Involvement of alpha-receptors in clonidine-induced inhibition of transmitter release from central monoamine neurones.

Authors:  K Starke; H Montel
Journal:  Neuropharmacology       Date:  1973-11       Impact factor: 5.250

7.  Evidence for a central noradrenaline receptor stimulation by clonidine.

Authors:  N E Andén; H Corrodi; K Fuxe; B Hökfelt; T Hökfelt; C Rydin; T Svensson
Journal:  Life Sci       Date:  1970-05-01       Impact factor: 5.037

8.  Clonidine-induced inhibition of sympathetic nerve activity: no indication for a central presynaptic or an indirect sympathomimetic mode of action.

Authors:  G Haeusler
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1974       Impact factor: 3.000

9.  Self-stimulation reward pathways: norepinephrine vs dopamine.

Authors:  L Stein; J D Belluzzi; S Ritter; C D Wise
Journal:  J Psychiatr Res       Date:  1974       Impact factor: 4.791

10.  Inhibition of adrenergic neurotransmission by clonidine: an action on prejunctional -receptors.

Authors:  K Starke; K P Altmann
Journal:  Neuropharmacology       Date:  1973-04       Impact factor: 5.250
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  3 in total

1.  Structural and steric requirements for beta-phenethylamines as agonists of the noradrenergic cyclic AMP generating system in the rat limbic forebrain.

Authors:  S E Robinson; P L Mobley; H E Smith; F Sulser
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1978-06       Impact factor: 3.000

2.  Effect of clonidine and phentolamine on self-stimulation behavior in the dorsal and ventral regions of the lateral hypothalamus in mice.

Authors:  P Cazala
Journal:  Psychopharmacology (Berl)       Date:  1980       Impact factor: 4.530

Review 3.  The Involvement of Norepinephrine in Behaviors Related to Psychostimulant Addiction.

Authors:  Magdalena Zaniewska; Małgorzata Filip; Edmund Przegalinski
Journal:  Curr Neuropharmacol       Date:  2015       Impact factor: 7.363
  3 in total

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