Literature DB >> 923720

Direct toxic effect of isoproterenol on cultured cardiac muscle cells.

E Severin, S Sartore, S Schiaffino.   

Abstract

Isoproterenol at relatively high doses (2.5 mg/ml) has a marked toxic effect on rat heart muscle cells cultivated in vitro. This effect is not prevented by propranolol and therefore is not mediated by beta adrenergic receptors.

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Year:  1977        PMID： 923720     DOI： 10.1007/bf01918826

Source DB:  PubMed          Journal:  Experientia        ISSN： 0014-4754


  9 in total

1.  Induction of necrosis and failure in the isolated perfused rat heart with oxidized isoproterenol.

Authors:  J C Yates; N S Dhalla
Journal:  J Mol Cell Cardiol       Date:  1975-11       Impact factor: 5.000

2.  ISOPROTERENOL-INDUCED MYOCARDIAL NECROSIS. A HISTOCHEMICAL AND ELECTRON MICROSCOPIC STUDY.

Authors:  V J FERRANS; R G HIBBS; W C BLACK; D G WEILBAECHER
Journal:  Am Heart J       Date:  1964-07       Impact factor: 4.749

3.  ISOPROTERENOL-INDUCED HEART NECROSIS, AN EXPERIMENTAL MODEL FOR THE STUDY OF ANGINA PECTORIS AND MYOCARDIAL INFARCT.

Authors:  G ZBINDEN; R E BAGDON
Journal:  Rev Can Biol       Date:  1963-06

Review 4.  STUDIES ON INFARCT-LIKE MYOCARDIAL NECROSIS PRODUCED BY ISOPROTERENOL: A REVIEW.

Authors:  G RONA; D S KAHN; C I CHAPPEL
Journal:  Rev Can Biol       Date:  1963-06

5.  An infarct-like myocardial lesion and other toxic manifestations produced by isoproterenol in the rat.

Authors:  G RONA; C I CHAPPEL; T BALAZS; R GAUDRY
Journal:  AMA Arch Pathol       Date:  1959-04

6.  Protective effects of propranolol on isoproterenol-induced myocardial infarction in arteriosclerotic and non-arteriosclerotic rats.

Authors:  B C Wexler
Journal:  Atherosclerosis       Date:  1973 Jul-Aug       Impact factor: 5.162

7.  Early alterations of the cardiac muscle cells in isoproterenol-induced necrosis.

Authors:  Z Csapó; J Dusek; G Rona
Journal:  Arch Pathol       Date:  1972-04

8.  Isoproterenol-induced cardiac necrosis.

Authors:  D S Kahn; G Rona; C I Chappel
Journal:  Ann N Y Acad Sci       Date:  1969-01-31       Impact factor: 5.691

9.  Permeability alteration of sarcolemmal membrane in catecholamine-induced cardiac muscle cell injury. In vivo studies with fine structural diffusion tracer horse radish peroxidase.

Authors:  M Boutet; I Hüttner; G Rona
Journal:  Lab Invest       Date:  1976-05       Impact factor: 5.662
  9 in total
  2 in total

1.  Myocardial cell damage and cardiovascular changes due to i.v. infusion of adrenochrome in rats.

Authors:  P K Singal; K S Dhillon; R E Beamish; N Kapur; N S Dhalla
Journal:  Br J Exp Pathol       Date:  1982-04

2.  Effects of physiologic mechanical stimulation on embryonic chick cardiomyocytes using a microfluidic cardiac cell culture model.

Authors:  Mai-Dung Nguyen; Joseph P Tinney; Fei Ye; Ahmed A Elnakib; Fangping Yuan; Ayman El-Baz; Palaniappan Sethu; Bradley B Keller; Guruprasad A Giridharan
Journal:  Anal Chem       Date:  2015-02-02       Impact factor: 6.986
  2 in total

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