| Literature DB >> 9237045 |
S Saarelainen1, E Seppälä, K Laasonen, J Hasan.
Abstract
Endothelin (ET)-1 is a potent vasoconstrictive and mitogenic peptide produced by endothelial cells and degraded predominantly in pulmonary vasculature. We measured ET-1 in 9-normotensive and 14 hypertensive men with obstructive sleep apnea. The ET-1 levels were higher in both normotensive (mean +/- SD, 6.3 +/- 2.8 pg/ml) and hypertensive (7.8 +/- 3.0 pg/ml) groups than in 66 healthy controls (2.9 +/- 1.2 pg/ml). Ten patients were restudied after three months of nCPAP treatment. No decrease in ET-1 was observed.Entities:
Mesh：
Substances：
Year: 1997 PMID： 9237045 DOI： 10.3109/10623329709079869
Source DB: PubMed Journal: Endothelium ISSN： 1026-793X