| Literature DB >> 9236509 |
S Hörner1, G Pasternak, R Hehlmann.
Abstract
The number of colony-forming cells (CFC) in the peripheral blood (PB) of 43 volunteers was examined using a semisolid clonogenic culture assay. In all, 22 male (age 21-39 years) and 21 female individuals (age 21-39 years) were tested, ten of each group twice to examine the intraindividual variability of colony-forming cells in PB. A statistically significant sex difference in the number of CFC, erythroblastic colonies (BFU-E), and granulocyte/macrophage colonies (CFU-GM) in PB was detected in favor of male individuals. No significant difference between female and male PB was found for the number of CFU-GEMM. The intraindividual variability of CFC and BFU-E was significantly higher in female donors. These results support previous reports by others on a potential influence of sex steroids on hematopoiesis.Entities:
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Year: 1997 PMID： 9236509 DOI： 10.1007/s002770050296
Source DB: PubMed Journal: Ann Hematol ISSN： 0939-5555 Impact factor: 3.673